April 26 – Chicago Cubs outfielder Jack McCarthy ties a major league record by starting three double plays in one game from the outfield.
June 13 – Christy Mathewson of the New York Giants tosses his second career no-hitter in a 1–0 victory against the Chicago Cubs.
June 29 – Archibald "Moonlight" Graham made his major league debut with the New York Giants during a game against the host Brooklyn Superbas at Washington Park. For the bottom of the eighth inning, Graham was sent in to play right field, replacing George Browne. In the top of the ninth, Graham was on deck when Claude Elliott flied out for the third and final out. Graham played the bottom of the ninth at right field but never came to bat, as the Giants won 11–1. That game turned out to be his only appearance in the major leagues. His story was popularized in Shoeless Joe, a novel by W. P. Kinsella, and the subsequent 1989 film Field of Dreams.
July 4 – In one of the greatest duels in baseball history, Cy Young and Rube Waddell go toe to toe in Boston. The A's and Waddell win 4–2 in 20 innings.
August 9 – Mistaking her husband for a burglar, the mother of minor league outfielder Ty Cobb shoots and kills him, an incident that will be cited as the reason for Cobb's intense desire to succeed. He will make his major league debut with the Tigers later this month.
September 6 – Frank Smith of the Chicago White Sox pitches a no-hitter in the second game of a doubleheader against the Detroit Tigers, as the Sox win 15–0.
October 14 – In Game 5 of the World Series, the New York Giants defeat the Philadelphia Athletics, 2–0, to claim their first world championship, four games to one.
October 22 – The Los Angeles Angels of the Pacific Coast League beats the visiting Portland Beavers, 3–2, in 11 innings. Los Angeles pitcher Bill Tozer ends his PCL record of 48 consecutive shutout inning-streak when Portland scored two unearned runs in the third inning.
January 18 – Fergy Malone, 63, Irish catcher and manager in a career that spanned 14 years from 1871 to 1884.
January 28 – Len Stockwell, 45, outfielder for the Cleveland Blues and Spiders teams.
February 6 – Ned Cuthbert, 59, outfielder who hit .254 with five teams between 1871 and 1884.
February 13 – Bill Eagan, 35, second baseman for three teams from 1891 to 1898.
February 13 – Ralph Ham, 55, outfielder for the 1871 Rockford Forest Citys.
February 18 – Tom Poorman, 47, outfielder for five teams from 1880 to 1888, who led American Association in triples and stolen bases in its 1887 season.
March 3 – Stump Weidman, 44, pitcher for nine seasons from 1880 to 1888, most notably for the Detroit Wolverines.
March 7 – John Murphy, 47, pitcher who posted a 5–12 record for the Altoona Mountain City and Wilmington Quicksteps in the 1884 season.
March 15 – Pete Meegan, 42, pitcher for two seasons, 1884 and 1885 with the Richmond Virginians and the Pittsburgh Alleghenys.
March 18 – Dick Higham, 53, English right fielder and catcher who led National League in doubles in its 1876 first season, in runs and doubles in 1878; later an umpire, barred from the sport in 1882.
March 22 – Gus Krock, 38, pitched from 1888 to 1890 for the Cubs, Hoosiers, Nationals and Bisons.
April–June[]
April 24 – Jim Gardner, 30, pitcher and infielder for the Pittsburgh Pirates/Orphans from 1895 to 1902.
April 25 – Jackie Hayes, 43, catcher/outfielder for seven different teams from 1882 to 1990.
July 28 – Harry Von der Horst, 54, former owner of the Baltimore Orioles and Brooklyn Superbas.
August 2 – George Snyder, 57, pitched briefly for the 1882 Philadelphia Athletics.
August 27 – Heinie Kappel, 41, infielder who hit a combined .269 for the Cincinnati Red Stockings (1887-88) and Columbus Solons (1899).
September 10 – Pete Browning, 44, legendary outfielder who helped to create the Louisville Slugger baseball bat and hit a .341 lifetime for the second-highest mark among right-handed hitters, who also won three batting titles and hit for the cycle twice, in a career that spanned from 1882 to 1894.