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The 1921 Ohio State Buckeyes football team represented Ohio State University in the 1921 Big Ten Conference football season. The Buckeyes compiled a 5–2 record while outscoring opponents 110–14. The 14 points allowed came in Ohio State's only losses. As of 2018, the Buckeyes' 1921 loss to Oberlin remains their last loss to a team from the state of Ohio.[citation needed]