On March 1, 1950, Frank Sinkwich was hired by Tampa to serve as the Spartans' head coach after the resignation of .[1] The season opened with a victory at Camp Lejeune and a loss against Jacksonville State before the Spartans won their first home game of the season against Wofford.[2] Tampa then won their next game over Stetson before they lost their second game of the season to Appalachian State.[3][4] After a pair of home victories over Livingston State and Delta State, Tampa closed the season with a pair of road losses. The first came against Marine Corps Base Quantico and the second against Florida State.[5]