The 1972 United States Senate election in Michigan was held on November 7, 1972. Incumbent Republican U.S. Senator and Senate Minority Whip Robert P. Griffin ran for re-election to a second term, won reelection defeating the Democratic candidate, and Michigan Attorney GeneralFrank J. Kelley. As of 2022, this is the last time that the Republicans have won Michigan’s Class 2 Senate seat, as well as the last time that a member of the party has been re-elected to either of the state’s Senate seats.