2-Quinolone
This article relies largely or entirely on a single source. (July 2017) |
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Preferred IUPAC name
Quinolin-2(1H)-one | |
Other names
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Identifiers | |
3D model (JSmol)
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ChEBI | |
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ECHA InfoCard | 100.000.382 |
EC Number |
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KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C9H7NO | |
Molar mass | 145.161 g·mol−1 |
Appearance | solid |
Melting point | 199.5 °C (391.1 °F; 472.6 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
2-Quinolone is an organic compound related structurally to quinoline. It is the majority tautomer in equilibrium with 2-quinolinol. The compound can be classified as a cyclic amide, and as such is used as an isostere for peptides and other pharmaceutically inspired targets.[1] The isomer 4-quinolone is the parent of a large class of quinolone antibiotics.
One example is .
References[]
- ^ Tashima, Toshihiko (2015). "The structural use of carbostyril in physiologically active substances". Bioorganic & Medicinal Chemistry Letters. 25 (17): 3415–3419. doi:10.1016/j.bmcl.2015.06.027. PMID 26112444.
External links[]
- Media related to 2-Quinolone at Wikimedia Commons
Categories:
- 2-Quinolones