The 13th Annual Nickelodeon Kids' Choice Awards was held on April 15, 2000, at the Hollywood Bowl in Los Angeles, live on Nickelodeon, with around 17,000 in attendance at the venue. Rosie O'Donnell hosted for the fifth consecutive year, along with LL Cool J, David Arquette, Mandy Moore, and Frankie Muniz as co-hosts. The show featured a SpongeBob SquarePants short to introduce the Favorite Cartoon nominees and announce the winner.
Over 15 million voters cast ballots for the ceremony, including for ten online-only categories.