ANKS1B

ANKS1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EAM, 2KE7, 2KIV, 2M38
Identifiers
Aliases	ANKS1B, AIDA, AIDA-1, ANKS2, EB-1, EB1, cajalin-2, ankyrin repeat and sterile alpha motif domain containing 1B
External IDs	OMIM: 607815 MGI: 1924781 HomoloGene: 51570 GeneCards: ANKS1B
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	90,973,300 bp
RNA expression pattern
	n/a
	More reference expression data
Gene ontology
Molecular function	ephrin receptor binding;
Cellular component	cytoplasm; cell junction; Cajal body; postsynaptic membrane; dendritic spine; cell projection; synapse; membrane; GO:0097483, GO:0097481 postsynaptic density; nucleus; cytosol; plasma membrane; intracellular membrane-bounded organelle;
Biological process	regulation of synaptic plasticity by receptor localization to synapse;
	Sources:Amigo / QuickGO
Orthologs
	56899
	77531
	ENSG00000185046
	ENSMUSG00000058589
	Q7Z6G8
	Q8BIZ1
NM_001204065; NM_001204066; NM_001204067; NM_001204068; NM_001204069;
	NM_001204070; NM_001204079; NM_001204080; NM_001204081; NM_020140; NM_152788; NM_181670
NM_001128086; NM_001177396; NM_001177397; NM_001177398; NM_181398;
	NM_001347053; NM_001347054; NM_001359240; NM_001359241; NM_001359242
NP_001190994; NP_001190995; NP_001190996; NP_001190997; NP_001190998;
	NP_001190999; NP_001191008; NP_001191009; NP_001191010; NP_064525; NP_690001; NP_858056; NP_001339114; NP_001339115; NP_001339116; NP_001339117; NP_001339118; NP_001339119; NP_001339120; NP_001339121; NP_001339122; NP_001339123; NP_001339124; NP_001339125; NP_001339126; NP_001339127; NP_001339128; NP_001339129; NP_001339130; NP_001339131; NP_001339132; NP_001339133; NP_001339134; NP_001339135; NP_001339136; NP_001339137; NP_001339138; NP_001339139; NP_001339140; NP_001339141; NP_001339142; NP_001339143; NP_001339145; NP_001339146; NP_001339147; NP_001339148; NP_001339149; NP_001339150; NP_001339151; NP_001339152; NP_001339153; NP_001339154
NP_001121558; NP_001170867; NP_001170868; NP_001170869; NP_001333982;
	NP_001333983; NP_852063; NP_001346169; NP_001346170; NP_001346171
	Wikidata
View/Edit Human	View/Edit Mouse

Ankyrin repeat and sterile alpha motif domain-containing protein 1B is a protein that in humans is encoded by the ANKS1B gene.^[4]^[5]^[6]

References[]

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058589 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fu X, McGrath S, Pasillas M, Nakazawa S, Kamps MP (Oct 1999). "EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1". Oncogene. 18 (35): 4920–9. doi:10.1038/sj.onc.1202874. PMID 10490826.
^ Wiemels JL, Leonard BC, Wang Y, Segal MR, Hunger SP, Smith MT, Crouse V, Ma X, Buffler PA, Pine SR (Nov 2002). "Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia". Proc Natl Acad Sci U S A. 99 (23): 15101–6. Bibcode:2002PNAS...9915101W. doi:10.1073/pnas.222481199. PMC 137550. PMID 12415113.
^ "Entrez Gene: ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B".

External links[]

Human AIDA genome location and AIDA gene details page in the UCSC Genome Browser.
Human ANKS1B genome location and ANKS1B gene details page in the UCSC Genome Browser.

Further reading[]

LeBrun DP (2004). "E2A basic helix-loop-helix transcription factors in human leukemia". Front. Biosci. 8 (1–3): s206–22. doi:10.2741/1030. PMID 12700034.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Petersen HH, Hilpert J, Militz D, et al. (2003). "Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule". J. Cell Sci. 116 (Pt 3): 453–61. doi:10.1242/jcs.00243. PMID 12508107.
Liu F, Su Y, Li B, Ni B (2003). "Regulation of amyloid precursor protein expression and secretion via activation of ERK1/2 by hepatocyte growth factor in HEK293 cells transfected with APP751". Exp. Cell Res. 287 (2): 387–96. doi:10.1016/S0014-4827(03)00152-6. PMID 12837293.
Ghersi E, Vito P, Lopez P, et al. (2004). "The intracellular localization of amyloid beta protein precursor (AbetaPP) intracellular domain associated protein-1 (AIDA-1) is regulated by AbetaPP and alternative splicing". J. Alzheimers Dis. 6 (1): 67–78. doi:10.3233/JAD-2004-6108. PMID 15004329.
Ghersi E, Noviello C, D'Adamio L (2005). "Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner". J. Biol. Chem. 279 (47): 49105–12. doi:10.1074/jbc.M405329200. PMID 15347684.
Xu H, Hebert MD (2006). "A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin". BMC Cell Biol. 6 (1): 23. doi:10.1186/1471-2121-6-23. PMC 1097723. PMID 15862129.
Meleshko AN, Belevtsev MV, Savitskaja TV, Potapnev MP (2007). "The incidence of T-cell receptor gene rearrangements in childhood B-lineage acute lymphoblastic leukemia is related to immunophenotype and fusion oncogene expression". Leuk. Res. 30 (7): 795–800. doi:10.1016/j.leukres.2005.11.007. PMID 16386788.

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[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000058589 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10490826-4] Fu X, McGrath S, Pasillas M, Nakazawa S, Kamps MP (Oct 1999). "EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1". Oncogene. 18 (35): 4920–9. doi:10.1038/sj.onc.1202874. PMID 10490826.

[pmid12415113-5] Wiemels JL, Leonard BC, Wang Y, Segal MR, Hunger SP, Smith MT, Crouse V, Ma X, Buffler PA, Pine SR (Nov 2002). "Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia". Proc Natl Acad Sci U S A. 99 (23): 15101–6. Bibcode:2002PNAS...9915101W. doi:10.1073/pnas.222481199. PMC 137550. PMID 12415113.

[entrez-6] "Entrez Gene: ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B".

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