ARHGAP27

ARHGAP27
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3PP2
Identifiers
Aliases	ARHGAP27, CAMGAP1, PP905, SH3D20, SH3P20, Rho GTPase activating protein 27
External IDs	OMIM: 610591 MGI: 1916903 HomoloGene: 45715 GeneCards: ARHGAP27
Gene location (Human)
Chr.	Chromosome 17 (human)
End	45,434,421 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	103,363,692 bp
Gene ontology
Molecular function	• SH3 domain binding; • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity;
Cellular component	• intracellular anatomical structure; • membrane; • nucleus; • nucleoplasm; • cytoplasm; • cytosol;
Biological process	• endocytosis; • signal transduction; • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity; • receptor-mediated endocytosis; • GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity;
	Sources:Amigo / QuickGO
Orthologs
	201176
	544817
	ENSG00000159314; ENSG00000276836; ENSG00000276907
	ENSMUSG00000034255
	Q6ZUM4; Q8N2Y9
	A2AB59
	NM_001159330; NM_001282290; NM_174919; NM_199282
	NM_001205236; NM_133715; NM_183288
	NP_001269219; NP_777579; NP_954976; NP_954976.1
	NP_001192165; NP_598476; NP_899111
	Wikidata
View/Edit Human	View/Edit Mouse

Rho GTPase activating protein 27 is a protein that in humans is encoded by the ARHGAP27 gene. ^[5]

Function[]

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may play a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013].

References[]

^ ^a ^b ^c ENSG00000276836, ENSG00000276907 GRCh38: Ensembl release 89: ENSG00000159314, ENSG00000276836, ENSG00000276907 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034255 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Rho GTPase activating protein 27". Retrieved 2018-05-30.

External links[]

PDBe-KB provides an overview of all the structure information available in the PDB for Human Rho GTPase-activating protein 27 (ARHGAP27)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by .

[refGRCh38Ensembl-1] ENSG00000276836, ENSG00000276907 GRCh38: Ensembl release 89: ENSG00000159314, ENSG00000276836, ENSG00000276907 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034255 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Rho GTPase activating protein 27". Retrieved 2018-05-30.

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