The human ARHGEF10gene encodes the proteinRho guanine nucleotide exchange factor 10.[5][6][7]
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals.[7]
^Mohl M, Winkler S, Wieland T, Lutz S (Aug 2006). "Gef10--the third member of a Rho-specific guanine nucleotide exchange factor subfamily with unusual protein architecture". Naunyn Schmiedebergs Arch Pharmacol. 373 (5): 333–41. doi:10.1007/s00210-006-0083-0. PMID16896804. S2CID29822779.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID15146197. S2CID27764390.