Archain 1

ARCN1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5A1U, 5A1V, 5A1W, 5A1X, 5A1Y
Identifiers
Aliases	ARCN1, COPD, archain 1, SRMMD
External IDs	OMIM: 600820 MGI: 2387591 HomoloGene: 1250 GeneCards: ARCN1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	118,603,033 bp
Gene ontology
Molecular function	• RNA binding;
Cellular component	• cytosol; • membrane; • Golgi membrane; • COPI-coated vesicle membrane; • transport vesicle; • endoplasmic reticulum; • COPI vesicle coat; • GO:0016023 cytoplasmic vesicle; • COPI-coated vesicle; • endoplasmic reticulum membrane; • cytoplasm; • Golgi apparatus;
Biological process	• retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; • cerebellar Purkinje cell layer maturation; • adult locomotory behavior; • endoplasmic reticulum to Golgi vesicle-mediated transport; • Golgi vesicle transport; • protein transport; • pigmentation; • intracellular protein transport; • vesicle-mediated transport; • transport; • Golgi localization;
	Sources:Amigo / QuickGO
Orthologs
	372
	213827
	ENSG00000095139
	ENSMUSG00000032096
	P48444
	Q5XJY5
	NM_001142281; NM_001655
	NM_145985
	NP_001135753; NP_001646
	NP_666097
	Wikidata
View/Edit Human	View/Edit Mouse

Archain 1 is a protein that in humans is encoded by the ARCN1 gene. ^[4]

Function[]

This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or vesicle trafficking.

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000095139 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Archain 1". Retrieved 2016-06-22.

Archain 1

Function[]

References[]

Further reading[]