Aviv Regev

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Aviv Regev
Aviv Regev ISMB 2017 (cropped).jpg
Aviv Regev at the Intelligent Systems for Molecular Biology conference in 2017
BornJuly 11, 1971[citation needed]
Alma materTel Aviv University (Ph.D.)
Awards
Scientific career
FieldsBioinformatics
Computational Biology
Institutions
Doctoral advisorEva Jablonka
Ehud Shapiro
Websitewww.broadinstitute.org/bios/aviv-regev Edit this at Wikidata

Aviv Regev (born July 11, 1971)[citation needed] is a computational biologist and Executive Vice President of Genentech Research and Early Development.[3] She was professor at the Broad Institute of MIT and Harvard and at the Department of Biology of the Massachusetts Institute of Technology,[4] as well as investigator at the Howard Hughes Medical Institute.[5] She and Sarah Teichmann lead the Human Cell Atlas project.[6]

Education[]

Regev studied at the Adi Lautman Interdisciplinary Program for Outstanding Students of Tel Aviv University, where she completed her Ph.D. under the supervision of Eva Jablonka[7] and Ehud Shapiro.[8]

Career and research[]

From 2020, Regev has been the Executive Vice President of Genentech Research and Early Development. She is based in South San Francisco.[9][10]

She served as the Core Institute Member, Chair of the Faculty and Co-director of the Cell Circuits Program at the Broad Institute.

Regev's research[11] includes work on gene expression[12][13] (with Eran Segal and David Botstein), and the use of π-calculus to represent biochemical processes.[14][15][16] Regev’s team has been a leading pioneer of single-cell genomics experimental and computational methods.[17]

Awards and honors[]

Regev was awarded the Overton Prize in 2008 for "outstanding accomplishment to a scientist in the early to mid stage of his or her career".[1] She was awarded the ISCB Innovator Award in 2017.[2][18] In 2008, she was also awarded the NIH Director's Pioneer Award.[19] She has also been awarded the Burroughs Wellcome Fund Career Award.[20] In 2017, she was awarded a Paul Marks Prize for Cancer Research.[21] She also served on the Life Sciences jury for the Infosys Prize in 2018. She was elected a member of the National Academy of Sciences (NAS) in 2019.[22] She was awarded the 25th Keio Medical Science Prize in 2020.[23]

References[]

  1. ^ Jump up to: a b Sansom, C.; Morrison Mckay, B. J. (2008). Bourne, Philip E. (ed.). "ISCB Honors David Haussler and Aviv Regev". PLOS Computational Biology. 4 (7): e1000101. Bibcode:2008PLSCB...4E0101S. doi:10.1371/journal.pcbi.1000101. PMC 2536508. PMID 18795145. open access
  2. ^ Jump up to: a b Fogg, Christiana N.; Kovats, Diane E.; Berger, Bonnie (2017). "2017 ISCB Innovator Award: Aviv Regev". PLOS Computational Biology. 13 (6): e1005558. Bibcode:2017PLSCB..13E5558F. doi:10.1371/journal.pcbi.1005558. ISSN 1553-7358. PMC 5493285. PMID 28665936. open access
  3. ^ GENENTECH EXECUTIVE COMMITTEE, accessed August 6, 2020.
  4. ^ "Aviv Regev at MIT". biology.mit.edu.
  5. ^ "Aviv Regev, PhD: Investigator / 2014–Present". hhmi.org. Howard Hughes Medical Institute.
  6. ^ Nowogrodzki, Anna (5 July 2017). "How to build a human cell atlas". Nature. 547 (7661): 24–26. doi:10.1038/547024a. Retrieved 11 December 2020.
  7. ^ Regev, A.; Lamb, M. J.; Jablonka, E. (1998). "The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense?". Molecular Biology and Evolution. 15 (7): 880. doi:10.1093/oxfordjournals.molbev.a025992. ISSN 0737-4038.
  8. ^ Regev, A.; Shapiro, E. (2002). "Cellular abstractions: Cells as computation". Nature. 419 (6905): 343. Bibcode:2002Natur.419..343R. doi:10.1038/419343a. PMC 3842595. PMID 12353013. closed access
  9. ^ Taylor, Nick Paul (May 11, 2020). "Genentech lures Regev from Broad Institute to lead research and early development". fiercebiotech.com. Retrieved 25 May 2020.
  10. ^ "Changes to the Roche Enlarged Corporate Executive Committee" (Press release). Basel, Switzerland: F. Hoffmann-La Roche Ltd. globenewswire. May 11, 2020. Retrieved 2020-05-25.
  11. ^ Search Results for author Regev A on PubMed.
  12. ^ Segal, E.; Shapira, M.; Regev, A.; Pe'er, D.; Botstein, D.; Koller, D.; Friedman, N. (2003). "Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data". Nature Genetics. 34 (2): 166–176. doi:10.1038/ng1165. PMID 12740579. S2CID 6146032.
  13. ^ Segal, E.; Friedman, N.; Koller, D.; Regev, A. (2004). "A module map showing conditional activity of expression modules in cancer". Nature Genetics. 36 (10): 1090–1098. doi:10.1038/ng1434. PMID 15448693. closed access
  14. ^ Regev, A.; Silverman, W.; Shapiro, E. (2001). "Representation and simulation of biochemical processes using the pi-calculus process algebra". Pacific Symposium on Biocomputing: 459–470. doi:10.1142/9789814447362_0045. ISBN 978-981-02-4515-3. PMID 11262964.
  15. ^ Priami, C.; et al. (2001). "Application of a stochastic name-passing calculus to representation and simulation of molecular processes" (PDF). Information Processing Letters. 80: 25–31. doi:10.1016/S0020-0190(01)00214-9. closed access
  16. ^ Study provides insight into regenerative potential of prostate gland, News Medical, accessed May 4, 2020.
  17. ^ "Aviv Regev". HHMI.org. Retrieved 2020-05-11.
  18. ^ "February 09, 2017: ISCB Announces 2017 Award Recipients". iscb.org. Retrieved 10 February 2017.
  19. ^ 2008 NIH Director’s Pioneer Award
  20. ^ Dynamic single-cell imaging of direct reprogramming reveals an early specifying event - Nature Biotechnology: Aviv Regev, Ph.D. - Career Awards at the Scientific Interface; Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs - Nature Biotechnology: Aviv Regev, Ph.D. - Career Awards at the Scientific Interface.
  21. ^ "2017 Prize Winners". Memorial Sloan Kettering Cancer Center. Retrieved 12 December 2017.
  22. ^ "2019 NAS Election". nasonline.org. Retrieved 30 April 2019.
  23. ^ "Award Ceremony for the 25th Keio Medical Science Prize". keio.ac.jp. Retrieved 22 December 2020.
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