BAM15
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Preferred IUPAC name
N5,N6-Bis(2-fluorophenyl)[2,1,3]oxadiazolo[4,5-b]pyrazine-5,6-diamine | |
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3D model (JSmol)
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Properties | |
C16H10F2N6O | |
Molar mass | 340.294 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
BAM15 is a novel mitochondrial protonophore uncoupler capable of protecting mammals from acute renal ischemic-reperfusion injury and cold-induced microtubule damage.[1][2]
References[]
- ^ Alexopoulos, Stephanie J.; Chen, Sing-Young; Brandon, Amanda E.; Salamoun, Joseph M.; Byrne, Frances L.; Garcia, Christopher J.; Beretta, Martina; Olzomer, Ellen M.; Shah, Divya P.; Philp, Ashleigh M.; Hargett, Stefan R.; Lawrence, Robert T.; Lee, Brendan; Sligar, James; Carrive, Pascal; Tucker, Simon P.; Philp, Andrew; Lackner, Carolin; Turner, Nigel; Cooney, Gregory J.; Santos, Webster L.; Hoehn, Kyle L. (2020). "Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice". Nature Communications. 11 (1): 2397. doi:10.1038/s41467-020-16298-2. PMC 7224297. PMID 32409697.
- ^ "A new study". medicalxpress. Retrieved 16 June 2020.
External links[]
Categories:
- Oxadiazoles
- Pyrazines
- Bicyclic compounds
- Fluoroarenes
- Anilines
- Secondary amines