BLUF domain
BLUF | |||||||||
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![]() structure of a cyanobacterial bluf protein, tll0078 | |||||||||
Identifiers | |||||||||
Symbol | BLUF | ||||||||
Pfam | PF04940 | ||||||||
InterPro | IPR007024 | ||||||||
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In molecular biology, the BLUF domain (sensors of blue-light using FAD) is a FAD-binding protein domain. They are present in various proteins, primarily from bacteria, for example a BLUF domain is found at the N-terminus of the AppA protein from Rhodobacter sphaeroides. The BLUF domain is involved in sensing blue-light (and possibly redox) using FAD and is similar to the flavin-binding PAS domains and cryptochromes. The predicted secondary structure reveals that the BLUF domain has a novel FAD-binding fold.[1]
References[]
- ^ Gomelsky M, Klug G (October 2002). "BLUF: a novel FAD-binding domain involved in sensory transduction in microorganisms". Trends in Biochemical Sciences. 27 (10): 497–500. doi:10.1016/s0968-0004(02)02181-3. PMID 12368079.
Categories:
- Protein domains