Cephaeline
Names | |
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Preferred IUPAC name
(1R)-1-{[(2S,3R,11bS)-3-Ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl]methyl}-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol | |
Other names
Cepheline; Desmethylemetine; Dihydropsychotrine
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.006.902 |
PubChem CID
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UNII | |
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Properties | |
C28H38N2O4 | |
Molar mass | 466.622 g·mol−1 |
Appearance | White silky crystals |
Solubility in ethanol | Soluble[vague] |
Hazards | |
Main hazards | Emetic / poisonous |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
what is ?) | (|
Infobox references | |
Cephaeline is an alkaloid that is found in Cephaelis ipecacuanha and other plant species including Psychotria acuminata.[1] Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac.[2] Chemically, it is closely related to emetine.
Poison treatment[]
Cephaeline in the form of syrup of ipecac was once commonly recommended as an emergency treatment for accidental poisoning, but its use has been phased out due to its ineffectiveness.[3]
References[]
- ^ Lara, Alfonso; Valverde, Roberto; Gomez, Luis; Hidalgo, Nancy (July 1, 2003). "Micropropagacion de la planta medicinal psychotria acuminata". Agronomía Costarricense. Retrieved 26 December 2009.
- ^ "Pharma Japan: Approval of 4 drugs including Seroquel recommended: CPAC panel". Chemical Business Newsbase. November 14, 2000. Retrieved 26 December 2009.
- ^ "Policy statement: Poison treatment in the home". Pediatrics. 112 (5): 1182–1185. November 2003. doi:10.1542/peds.112.5.1182. PMID 14595067. Archived from the original on 2010-07-06. Retrieved 31 December 2009.
Categories:
- Isoquinoline alkaloids
- Phenols
- Norsalsolinol ethers
- Emetics