Collins oxidation

From Wikipedia, the free encyclopedia
Collins oxidation
Named after Joseph C. Collins
Reaction type Organic redox reaction
Identifiers
RSC ontology ID RXNO:0000550

The Collins oxidation is an organic reaction for the oxidation of primary alcohols to aldehydes. It is distinguished from other chromium oxide-based oxidations by the use of Collins reagent, a complex of chromium(VI) oxide with pyridine in dichloromethane.[1][2]

Alcohol oxidation with Collins reagent.svg

Related oxidation reactions[]

Several chromium oxides are used for related oxidations.[3] These include Jones oxidation and Sarett oxidation.

See also[]

References[]

  1. ^ J. C. Collins, W. W. Hess and F. J. Frank (1968). "Dipyridine-chromium(VI) oxide oxidation of alcohols in dichloromethane". Tetrahedron Lett. 9 (30): 3363–3366. doi:10.1016/S0040-4039(00)89494-0.
  2. ^ J. C. Collins, W.W. Hess (1988). "Aldehydes from Primary Alcohols by Oxidation with Chromium Trioxide: Heptanal". Organic Syntheses.; Collective Volume, vol. 6, p. 644
  3. ^ Smith, Michael B.; March, Jerry (2007), Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (6th ed.), New York: Wiley-Interscience, ISBN 978-0-471-72091-1
Retrieved from ""