Cunninghamella
| Cunninghamella | |
|---|---|
| |
| Cunninghamella echinulata | |
Scientific classification 
| |
| Kingdom: | Fungi |
| Phylum: | Mucoromycota |
| Order: | Mucorales |
| Family: | Cunninghamellaceae |
| Genus: | Cunninghamella Matr. (1903) |
| Type species | |
| Cunninghamella africana Matr. 1903
| |
| Species | |
|
See text | |
| Synonyms[1] | |
| |
Cunninghamella is a genus of fungi in the order Mucorales, and the family Cunninghamellaceae.[2] The genus was circumscribed by French mycologist Alphonse Louis Paul Matruchot in 1903.[3]
Species[]
As of 2015, Index Fungorum lists 13 valid species of Cunninghamella:[4]
- Cunninghamella binarieae 2001
- Cunninghamella blakesleeana
- 1929
- Cunninghamella clavata & 1998
- Cunninghamella echinulata (Thaxt.) Thaxt. ex Blakeslee 1905
- Cunninghamella elegans 1905
- Cunninghamella homothallica & 1952
- Cunninghamella intermedia & 1966
- Cunninghamella multiverticillata & 2001
- Cunninghamella phaeospora Boedijn 1959
- Cunninghamella polymorpha 1929
- Cunninghamella septata 2001
- Cunninghamella vesiculosa 1966
Uses[]
Members of this genus are often used in studies investigating the metabolism of drugs, because these species metabolize a wide range of drugs in manners similar to mammalian enzyme systems.[5] Many species are also capable of oxidizing polycyclic aromatic hydrocarbons, a class of stable organic molecules that tends to persist in the environment and contains many known carcinogenic and mutagenic compounds.[6]
The presence of a cytochrome P450 has been demonstrated in C. bainieri.[7]
References[]
- ^ "Synonymy: Cunninghamella Matr". Species Fungorum. CAB International. Retrieved 21 September 2015.
- ^ Cunninghamella at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Matruchot L. (1903). "Une Mucorinée purement conidienne. Cunninghamella africana". Annales Mycologici (in French). 1: 45–60.
- ^ "Species Fungorum (version 26th August 2015). In: Species 2000 & ITIS Catalogue of Life". Retrieved 21 September 2015.
- ^ Asha S, Vidyavathi M (2009). "Cunninghamella--a microbial model for drug metabolism studies--a review". Biotechnol. Adv. 27 (1): 16–29. doi:10.1016/j.biotechadv.2008.07.005. PMID 18775773.
- ^ Cerniglia, Carl E. (1992). "Biodegradation of polycyclic aromatic hydrocarbons". Biodegradation. 3 (2–3): 351–368. doi:10.1007/BF00129093.
- ^ Aryl hydrocarbon hydroxylase activity in the fungus Cunninghamella bainieri: Evidence for the presence of cytochrome P-450. J.P. Ferris, L.H. MacDonald, M.A. Patrie and M.A. Martin, Archives of Biochemistry and Biophysics, Volume 175, Issue 2, August 1976, pages 443-452, doi:10.1016/0003-9861(76)90532-4
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