Edwin C. Webb

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Edwin Clifford Webb
Edwin C. Webb.png
Vice-Chancellor of Macquarie University
In office
1976–1986
Preceded by
Succeeded byDianne Yerbury
Personal details
Born1921
Dorset
Died2006
Alma materClare College, Cambridge
OccupationAcademic
ProfessionBiochemist

Edwin Clifford Webb (1921–2006) was a biochemist. He studied nerve gases at the University of Cambridge where he was a Beit Fellow and lecturer. He had earned his doctorate there, working in the laboratory of Malcolm Dixon and continued to collaborate with him in the study of enzymes. Together, they wrote a classic textbook on the subject, Enzymes, which was first published by Longmans in 1958,[1] He then took a chair in biochemistry[2] at the University of Queensland but continued to collaborate with Dixon on further editions.[3][4] In 1970, he became the Deputy Vice-Chancellor at Queensland and in 1975 he became the second Vice-Chancellor of Macquarie University. He retired in 1986 but continued to work on the enzyme list of the International Union of Biochemistry and Molecular Biology (IUBMB) while living in Townsville.[5]​

Research[]

Cambridge[]

Webb's first paper was written with Kenneth Bailey on yeast pyrophosphatase,[6] the first of many papers on enzymes. It was followed by several papers on nerve gases, for example on British anti-lewisite with Ruth van Heyningen.[7] Research collaboration with Malcolm Dixon began with a study of phosphotransferases,[8] and continued with other work, both theoretical[9] and experimental.

Queensland[]

After moving to Queensland Webb collaborated with Burt Zerner on Jack bean urease, starting with a study of its purification and assay,[10] followed by other papers on the same enzyme. He also worked with Zerner on other enzymes, including carboxylesterases.

Nomenclature[]

Webb's interest in biochemical nomenclature started early in his career,[11] and after the IUBMB compilation was published for the last time as a printed book[12] he wrote a retrospective article about it.[13]

References[]

  1. ^ Dixon, M; Webb, EC (1958). Enzymes (1st ed.). London: Longmans, Green, and Co.
  2. ^ "Professor Emeritus Edwin Webb FRACI". 8 January 2016.
  3. ^ Dixon, M; Webb, EC (1964). Enzymes (2nd ed.). London: Longmans, Green, and Co.
  4. ^ Dixon, M; Webb, EC; Thorne, CJR; Tipton, KF (1979). Enzymes (3rd ed.). London: Longmans Group. ISBN 978-0122183584.
  5. ^ (December 2006), "Edwin Clifford Webb", IUBMB Life, 58 (12): 734–736, doi:10.1080/15216540601055356
  6. ^ Bailey, K; Webb, EC (1944). "Purification and Properties of Yeast Pyrophosphatase". Biochem. J. 38 (5): 394–398. doi:10.1042/bj0380394. PMC 1258115. PMID 16747821.
  7. ^ Webb, EC; van Heyningen, R (1947). "The action of British anti-lewisite (BAL) on enzyme systems". Biochem. J. 41 (1): 74–78. doi:10.1042/bj0410074. PMC 1258426. PMID 16748122.
  8. ^ Dixon, M.; Webb, E. C. (1953). "Phosphate-Transferring Enzymes". British Medical Bulletin. 9 (2): 110–115. doi:10.1093/oxfordjournals.bmb.a074324. PMID 13059393.
  9. ^ Dixon, M; Webb, E C (1961). "Enzyme fractionation by salting-out – a theoretical note". Advances in Protein Chemistry. 16: 197–219. doi:10.1016/S0065-3233(08)60030-3. ISBN 9780120342167. PMID 14028133.
  10. ^ Blakeley, Robert L.; Webb, Edwin C.; Zerner, Burt (1969). "Jack bean urease (EC 3.5.1.5). A new purification and reliable rate assay". Biochemistry. 8 (5): 1984–1990. doi:10.1021/bi00833a031. PMID 4977580.
  11. ^ Webb, E C. "Communication in Biochemistry". Nature. 225 (5228): 132–135. doi:10.1038/225132a0.
  12. ^ Webb, Edwin C. (10 September 1992). Enzyme Nomenclature 1992: Recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology and the Nomenclature and Classification of Enzymes. Orlando: Academic Press. ISBN 978-0122271649.
  13. ^ Webb, E C (1993). "Enzyme Nomenclature - a personal retrospective". FASEB J. 7 (12): 1192–1194. doi:10.1096/fasebj.7.12.8375619. PMID 8375619. S2CID 9678760.
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