Film coating
 | This article has multiple issues. Please help or discuss these issues on the talk page. (Learn how and when to remove these template messages)
|
A film coating is a thin polymer-based coat applied to a solid pharmaceutical dosage form such as a tablet. The thickness of such a coating is typically between 20-100 µm.[1][irrelevant citation] It is possible to follow the dynamic curing effect on tablet coating structure by using non-destructive analytical methodologies.[2]
Film coatings are frequently applied in orally-administered pharmaceuticals. The motivation for applying film coatings to dosage forms range from cosmetic considerations such as colour, gloss and branding, improving the shelf life by providing a protective barrier between the drug and the surrounding environment, and making the dosage form easier to swallow. They may also be used to delay or augment the delivery and uptake of medications, such as in modified- or sustained-release dosage, or delay release and uptake until the medication passes through the stomach, as in enteric coatings.
Film coating formulations typically contain the following components:
- Polymer
- Plasticizer
- Colourant
- Opacifier
- Solvent
- Vehicle
References[]
- ^ Felton, Linda A; Porter, Stuart C (2013). "An update on pharmaceutical film coating for drug delivery". Expert Opinion on Drug Delivery. 10 (4): 421–35. doi:10.1517/17425247.2013.763792. PMID 23339342. S2CID 34820042.
- ^ Gendre C., Genty M., César da Silva J., Tfayli A., Boiret M., Lecoq O., Baron M., Chaminade P., Péan J-M., Comprehensive study of dynamic curing effect on tablet coating structure, Eur. J. Pharm. Biopharm., 81 (2012), 657-665
 | This pharmacy-related article is a stub. You can help Wikipedia by . |
- Pharmacology stubs
- Pharmacy
- Coatings
- Polymers