Friedreich's sign

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Friedreich's sign
Differential diagnosisconstrictive pericarditis

In medicine, Friedreich's sign is the exaggerated drop in diastolic central venous pressure seen in constrictive pericarditis (particularly with a stiff calcified pericardium) and manifested as abrupt collapse of the neck veins or marked descent of the central venous pressure waveform.[citation needed]

The sign is named after Nikolaus Friedreich.[1]

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