GSDMC

GSDMC
Identifiers
Aliases	GSDMC, MLZE, gasdermin C
External IDs	OMIM: 608384 MGI: 2146102 HomoloGene: 69487 GeneCards: GSDMC
Gene location (Human)
Chr.	Chromosome 8 (human)
End	129,786,624 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	63,717,026 bp
RNA expression pattern
	Top expressed in
	zone of skin; ; quadriceps femoris muscle; ; spleen; ; esophagus;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function; phosphatidylserine binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding;
Cellular component	cytoplasm; mitochondrion; microtubule organizing center; cytosol; plasma membrane; membrane;
Biological process	programmed cell death; biological process; pyroptosis;
	Sources:Amigo / QuickGO
Orthologs
	56169
	331063
	ENSG00000147697; ENSG00000285114
	ENSMUSG00000056293
	Q9BYG8
	Q2KHK6
	NM_031415
	NM_001168274; NM_177912
	NP_113603
	NP_001161746; NP_808580
	Wikidata
View/Edit Human	View/Edit Mouse

Gasdermin C is a protein that in humans is encoded by the GSDMC gene. ^[5]

References[]

^ ^a ^b ^c ENSG00000285114 GRCh38: Ensembl release 89: ENSG00000147697, ENSG00000285114 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056293 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Gasdermin C". Retrieved 2016-08-26.

Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, Yanagihara K, Ogawa K, Sakamoto H, Yoshida T, Sasaki H (2009). "Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium". Genes Chromosomes Cancer. 48 (3): 261–71. doi:10.1002/gcc.20636. PMID 19051310. S2CID 19705164.

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