GUK1

GUK1
Identifiers
Aliases	GUK1, GMK, guanylate kinase 1
External IDs	OMIM: 139270 MGI: 95871 HomoloGene: 665 GeneCards: GUK1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	228,148,984 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	59,083,038 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; dorsolateral prefrontal cortex; ; amygdala; ; hippocampus proper; ; corpus callosum; ; substantia nigra; ; Brodmann area 9;
	More reference expression data
	n/a
Gene ontology
Molecular function	ATP binding; kinase activity; nucleotide binding; transferase activity; guanylate kinase activity;
Cellular component	cytosol;
Biological process	dGMP metabolic process; purine nucleotide metabolic process; nucleobase-containing small molecule interconversion; glycoprotein transport; GMP metabolic process; ATP metabolic process; nucleotide phosphorylation; GDP biosynthetic process; dGDP biosynthetic process; dATP metabolic process; phosphorylation; GDP-mannose metabolic process; GDP metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	2987
	14923
	ENSG00000143774
	ENSMUSG00000020444
	Q16774; Q6IBG8
	Q64520
	NM_000858; NM_001159390; NM_001159391; NM_001242839; NM_001242840
	NM_001159410; NM_008193
NP_000849; NP_001152862; NP_001152863; NP_001229768; NP_001229769;
	NP_000849.1; NP_001152862.1; NP_001152863.1; NP_001229768.1
	NP_001152882; NP_032219
	Wikidata
View/Edit Human	View/Edit Mouse

Guanylate kinase is an enzyme that in humans is encoded by the GUK1 gene.^[5]^[6]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143774 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020444 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fitzgibbon J, Katsanis N, Wells D, Delhanty J, Vallins W, Hunt DM (Jul 1996). "Human guanylate kinase (GUK1): cDNA sequence, expression and chromosomal localisation". FEBS Lett. 385 (3): 185–188. doi:10.1016/0014-5793(96)00365-1. PMID 8647247.
^ "Entrez Gene: GUK1 guanylate kinase 1".

Overview of all the structural information available in the PDB for UniProt: Q16774 (Human Guanylate kinase) at the PDBe-KB.
Overview of all the structural information available in the PDB for UniProt: Q64520 (Mouse Guanylate kinase) at the PDBe-KB.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by .