"Girls & Boys" is the third single taken from Good Charlotte's second studio album, The Young and the Hopeless (2002). It was released in Europe on April 28, 2003, and was released in the United States and Australia later in the year. The song peaked at number 48 on the US Billboard Hot 100. Outside the US, "Girls and Boys" peaked at number six in the United Kingdom and topped the UK Rock Chart. The song eventually received a Silver certification from the British Phonographic Industry for selling at least 200,000 copies. Elsewhere, "Girls & Boys" reached the top 40 in Australia, Ireland, and New Zealand.
The music video for the song predominantly shows geriatric people dressed and acting like young people. The various members of the band are shown interacting with the older characters (for example playing video games and giving massages). At the end of the video, Benji Madden wakes up to find an old woman wearing one of his shirts and offering him a bowl of cereal.
The video for "Girls & Boys" was shot in the suburb of Ellerslie in Auckland, New Zealand. The longer version includes dialogue of a senior woman and the band, a parodying reference to Avril Lavigne's video "Complicated".