Goldstein's toe sign
| Goldstein's toe sign | |
|---|---|
| Differential diagnosis | Down syndrome or cretinism |
"Goldstein's Toe Sign" is a feature identified by Dr. Hyman Isaac Goldstein (1887–1954), an American physician and medical historian. A greater distance separates the largest two toes of some people exhibiting Down syndrome or cretinism."[1]
References[]
Wide distance between the great toe and the adjoining toe; associated with cretinism and trisomy 21.
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