HL23V
HL23V was reputedly a type C RNA tumor virus first isolated in 1975 from cultured human acute myelogenous leukaemia peripheral blood leukocytes, which would have been the first cancer-causing retrovirus isolated from human sera.[1] It was later shown to be a laboratory contaminant of three monkey viruses. The journal Nature, which had published the original research, later retracted the article.
See also[]
- Simian sarcoma associated virus (SSAV or SSAV-1), one of two associated viruses comprising HL23V
- HTLV-1, the actual first human pathogenic retrovirus discovered in 1981
References[]
- ^ Chan, E.; Peters, W.; Sweet, R.; Ohno, T.; Kufe, D.; Spiegelman, S.; Gallo, R.; Gallagher, R. (1976). "Characterisation of a virus (HL23V) isolated from cultured acute myelogenous leukaemic cells". Nature. 260 (5548): 266–268. Bibcode:1976Natur.260..266C. doi:10.1038/260266a0. PMID 176596. S2CID 1774802.; Gallagher, R.; Gallo, R. (1975). "Type C RNA tumor virus isolated from cultured human acute myelogenous leukemia cells". Science. 187 (4174): 350–3. Bibcode:1975Sci...187..350G. doi:10.1126/science.46123. PMID 46123.
Further reading[]
- Science Fictions: A Scientific Mystery, a Massive Cover-up, and the Dark Legacy of Robert Gallo ISBN 0316090042, 2002, John Crewdson
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