HLA-B55




major histocompatibility complex (human), class I, B55
Alleles	B5501, B5502
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*5501
	B*5502
Locus	chr.6 6p21.31

HLA-B55 (B55) is an HLA-B serotype. B55 is a from the B22 , sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products.^[1] (For terminology help see: HLA-serotype tutorial)

Serotype[]

B*55:03 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*73:01.^[2]

B55 and B22 serotype recognition of some HLA B*55 allele-group gene products^[3]
B*55	B55	B22	Sample
allele	%	%	size (N)
5501	92	5	453
5502	84	2	309

Allele distribution[]

**HLA B*5501 frequencies**
		freq
ref.	Population	(%)
^[4]	India New Delhi	3.8
^[4]	Singapore Chinese Han	3.5
^[4]	Spain Eastern Andalusia Gipsy	3.5
^[4]	Georgia Tbilisi Kurds	3.4
^[4]	India North Delhi	3.3
^[4]	France South East	3.1
^[4]	Israel Arab Druse	3.0
^[4]	India North Hindus	2.9
^[4]	Georgia Tbilisi Georgians	2.8
^[4]	Russia Tuva (2)	2.8
^[4]	Georgia Svaneti Svans	2.5
^[4]	Iran Baloch	2.5
^[4]	Singapore Thai	2.5
^[4]	Sudanese	2.5
^[4]	Mexico Mestizos	2.4
^[4]	Spain Eastern Andalusia	2.4
^[4]	Ireland South	2.0
^[4]	Azores Central Islands	1.8
^[4]	Bulgaria	1.8
^[4]	Israel Ashkenazi and Non Ashkenazi Jews	1.8
^[4]	Oman	1.7
^[4]	Tunisia Tunis	1.7
^[4]	India Andhra Pradesh Golla	1.4
^[4]	China Tibet	1.3
^[4]	Uganda Kampala	1.2
^[4]	Finland	1.1
^[4]	Portugal North	1.1
^[4]	Portugal Centre	1.0
^[4]	Singapore Riau Malay	1.0
^[4]	*B5502**
^[4]	Taiwan Taroko	14.5
^[4]	American Samoa	12.0
^[4]	China Guangxi Maonan	6.0
^[4]	Japan Ainu Hokkaido	5.0
^[4]	China Tibet Autonomous Region Tibetans	4.7
^[4]	Singapore Chinese	3.0
^[4]	China Beijing Shijiazhuang Tianjian Han	2.9
^[4]	China North Han	2.9
^[4]	South Korea (3)	2.7
^[4]	Hong Kong Chinese	2.2
^[4]	Japan (5)	2.2
^[4]	Taiwan Ami	2.0
^[4]	Thailand (3)	2.0
^[4]	New Caledonia	1.0
^[4]	Philippines Ivatan	1.0

References[]

^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
^ Voorter, CE; van der Vlies, S; Kik, M; van den Berg-Loonen, EM (October 2000). "Unexpected Bw4 and Bw6 reactivity patterns in new alleles". Tissue Antigens. 56 (4): 363–70. doi:10.1034/j.1399-0039.2000.560409.x. PMID 11098937.
^ derived from IMGT/HLA
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x ^y ^z ^aa ^ab ^ac ^ad ^ae ^af ^ag ^ah ^ai ^aj ^ak ^al ^am ^an ^ao ^ap ^aq ^ar ^as Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. {{cite journal}}: External link in |title= (help)

[pmid15787720-1] Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.

[2] Voorter, CE; van der Vlies, S; Kik, M; van den Berg-Loonen, EM (October 2000). "Unexpected Bw4 and Bw6 reactivity patterns in new alleles". Tissue Antigens. 56 (4): 363–70. doi:10.1034/j.1399-0039.2000.560409.x. PMID 11098937.

[3] rived from IMGT/HLA

[pmid12753660-4] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x ^y ^z ^aa ^ab ^ac ^ad ^ae ^af ^ag ^ah ^ai ^aj ^ak ^al ^am ^an ^ao ^ap ^aq ^ar ^as Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. {{cite journal}}: External link in |title= (help)

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