HN1 (gene)

JPT1
Identifiers
Aliases	JPT1, ARM2, HN1A, HN1, hematological and neurological expressed 1, Jupiter microtubule associated homolog 1
External IDs	MGI: 1096361 HomoloGene: 7364 GeneCards: JPT1
Gene location (Human)
Chr.	Chromosome 17 (human)
End	75,168,281 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	115,405,213 bp
RNA expression pattern
	Top expressed in
	prosencephalon; ; testicle; ; neocortex; ; cerebral cortex; ; brain;
	More reference expression data
	More reference expression data
Orthologs
	51155
	15374
	ENSG00000189159
	ENSMUSG00000020737
	Q9UK76
	P97825
NM_001002032; NM_001002033; NM_001288609; NM_001288610; NM_001288611;
	NM_016185
	NM_008258
NP_001002032; NP_001002033; NP_001275538; NP_001275539; NP_001275540;
	NP_057269
	NP_032284
	Wikidata
View/Edit Human	View/Edit Mouse

Hematological and neurological expressed 1 protein is a protein that in humans is encoded by the HN1 gene.^[5]^[6]

NOTE: HN1 can also refer to the Notch 1 gene.

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000189159 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020737 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhou G, Wang J, Zhang Y, Zhong C, Ni J, Wang L, Guo J, Zhang K, Yu L, Zhao S (Apr 2004). "Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family". Gene. 331: 115–23. doi:10.1016/j.gene.2004.02.025. PMID 15094197.
^ "Entrez Gene: HN1 hematological and neurological expressed 1".

Further reading[]

Laughlin KM, Luo D, Liu C, Shaw G, Warrington KH Jr, Law BK, Harrison JK (2009). "Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest". Differentiation. 78 (1): 35–44. doi:10.1016/j.diff.2009.04.001. PMC 2867035. PMID 19427096.
Laughlin KM, Luo D, Liu C, Shaw G, Warrington KH Jr, Qiu J, Yachnis AT, Harrison JK (2009). "Hematopoietic- and Neurologic-Expressed Sequence 1 Expression in the Murine GL261 and High-Grade Human Gliomas". Pathol Oncol Res. 15 (3): 437–44. doi:10.1007/s12253-008-9147-4. PMC 2819207. PMID 19145478.
Zujovic V, Luo D, Baker HV, Lopez MC, Miller KR, Streit WJ, Harrison JK (2005). "The facial motor nucleus transcriptional program in response to peripheral nerve injury identifies Hn1 as a regeneration-associated gene". J Neurosci Res. 82 (5): 581–91. doi:10.1002/jnr.20676. PMID 16267826. S2CID 5545114.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Zougman A, Wiśniewski JR (2006). "Beyond linker histones and high mobility group proteins: global profiling of perchloric acid soluble proteins". J. Proteome Res. 5 (4): 925–34. doi:10.1021/pr050415p. PMID 16602700.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Li D, Gonzalez O, Bachinski LL, Roberts R (2001). "Human protein tyrosine phosphatase-like gene: expression profile, genomic structure, and mutation analysis in families with ARVD". Gene. 256 (1–2): 237–43. doi:10.1016/S0378-1119(00)00347-4. PMID 11054553.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by .

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000189159 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020737 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15094197-5] Zhou G, Wang J, Zhang Y, Zhong C, Ni J, Wang L, Guo J, Zhang K, Yu L, Zhao S (Apr 2004). "Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family". Gene. 331: 115–23. doi:10.1016/j.gene.2004.02.025. PMID 15094197.

[entrez-6] "Entrez Gene: HN1 hematological and neurological expressed 1".

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