Intracellular receptor
This article may be too technical for most readers to understand.(June 2020) |
Intracellular receptors are receptors located inside the cell rather than on its cell membrane. Classic hormones that use intracellular receptors include thyroid and steroid hormones. Examples are the class of nuclear receptors located in the cell nucleus and cytoplasm and the IP3 receptor located on the endoplasmic reticulum. The ligands that bind to them are usually intracellular second messengers like inositol trisphosphate (IP3) and extracellular lipophilic hormones like steroid hormones. Some intracrine peptide hormones also have intracellular receptors.
Examples[]
- transcription factors
- nuclear receptors
- other
- Sigma1 (neurosteroids)
- IP3 receptor (inositol triphosphate, IP3)
See also[]
- Receptor
- Steroid hormone
External links[]
- Nuclear Receptor journal homepage
- Nuclear receptor resource at Georgetown University
- Nuclear receptor signalling atlas (NURSA, open-access journal)
Categories:
- Intracellular receptors