Kendall Smith

Kendall A. Smith Kendall A. Smith is an American scientist most well-known for his work on interleukins, the regulatory molecules of the immune system, which has led to many of the new present-day therapies for immunological disorders, transplant rejection, infectious diseases and cancer.^[1]^[2] Smith is a Professor Emeritus of Medicine at Weill Cornell Medicine.^[3]

Early life[]

Kendall Arthur Smith was born in Akron, Ohio, where he grew up as the second child of Robert Lyman Smith and Juanita Murphy Smith. He attended Fairlawn Primary School, Simon Perkins Junior High School followed by Buchtel High School in Akron, graduating in 1960.

Medical and scientific training[]

Smith graduated from Denison University, Granville, Ohio with a B.S. in biology (1964).^[4] He graduated summa cum laude from the Ohio State University College of Medicine in 1968, then trained in Internal Medicine at Yale-New Haven Hospital (1968-1970). Smith then trained at the National Cancer Institute, Dartmouth Medical School and L’Institut de Cancerologie et d’Immunogenetique in Villejuif, France (1970-’74).

Career[]

Smith joined the faculty of Dartmouth Medical School (Hanover, N.H.) as an Assistant Professor of Medicine in Hematology & Oncology in 1974, progressing to Associate Professor (1978) and Professor (1982).

In 1993 Smith moved to Weill Cornell Medicine in New York City to conduct clinical research in AIDS. There he served as the Chief of The Division of Immunology as well as the Co-Chair of the Immunology Program of The Graduate School of Biomedical Sciences, a joint program between Cornell and Sloan-Kettering Institute. He also served as the Director of The Tr-Institutional MD/PhD Program, a joint effort between Cornell, Sloan-Kettering and the Rockefeller University.

Publications[]

Molecular Immunity: A Chronology of 60 Years of Discovery, ISBN 9789813231702, World Scientific Publishing Company, 2018^[5]
The Interleukin 2 Receptor, Academic Press, New York, 1988^[6]
The Quantal Theory of Immunity: The molecular Basis of Autoimmunity and Leukemia. World Scientific Publishing Co. Pte. Singapore, 2008^[7]
Molecular Immunity: A Chronology of 60 Years of Discovery, ISBN 9789813231702, World Scientific Publishing Co. Pte., 2018

Honors and awards[]

1965 Nu Sigma Nu Award for the Outstanding First year Medical Student
1966 The Chauncy Leake Award
1967 Alpha Omega Alpha - Scholastic Honorary Society
1968 Landacre Society – Student Research Honorary Society, President
1968 Robert Nelson Watman Award for Outstanding Achievement in Research and Medicine
1968 M.D. summa cum laude
1979 Elected as Fellow to the American College of Physicians
1981 Elected to the American Society for Clinical Investigation
1989 Friedrich-Sasse Foundation Award
1993 Denison University Alumni Citation Award
2009 Alumni Achievement Award, The Ohio State University College of Medicine

Journals[]

The generation of the first antigen-specific functional monoclonal T cells, Nature, 268:154-156, 1977.
The creation of the T cell Growth Factor (IL2) bioassay, 1978
The Scientific Rationale For The Interleukin Nomenclature, . J. Exp. Med. l5l:l55l-l556, 1980
The biochemical characterization of the IL-2 molecule, Mol. Immunol. 18:1087-1094, 1981
The demonstration that memory T cells are differentiated cytokine producers, Med., 173:25-36, 1991.
The development of a new nontoxic dosing regimen for IL-2 immunotherapy, Proc. Natl. Acad. Sci. U.S.A. 93:10,405-10,410, 1996.
Therapeutic Use Of IL2 To Enhance Antiviral T Cell Responses In Vivo. Nature Med. 9:1-8, 2003