Lactase-like is a protein that in humans is encoded by the LCTL gene.[5] Lactase-like is a glycosidaseenzyme.
Function[]
This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyzeglycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acidresidues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Ito S, Fujimori T, Hayashizaki Y, Nabeshima Y (July 2002). "Identification of a novel mouse membrane-bound family 1 glycosidase-like protein, which carries an atypical active site structure". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1576 (3): 341–5. doi:10.1016/S0167-4781(02)00281-6. PMID12084582.
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