LacED

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The Lactase Engineering Database
Content
DescriptionDatabase of Beta-lactamases that allows reconciliation of TEM Beta-lactamase information against NCBI
Data types
captured		Beta-lactamase
OrganismsBacteria
Contact
Primary citationPMID 19698099
Access
Websitewww.laced.uni-stuttgart.de
Miscellaneous
Bookmarkable
entities		yes

LacED, also known as The Lactamase Engineering Database is a database that identifies and corrects inconsistencies in already existing databases, namely Beta-lactamases. It integrates such information as mutations, sequence alignments, and structures in order to accomplish the task.[1] As of the publication of the primary literature, LacED provides 2399 sequences entries and 37 structure entries.[1] Example of this database in action is shown when 89 proteins from the microbial organisms and 35 proteins from cloning or expression vectors had new mutation profiles.[1] Additionally, 55 proteins had inconsistent annotations in their TEM assignments or mutation profiles.[1]

See also[]

  • Antimicrobial Resistance databases

References[]

  1. ^ a b c d Thai, Quan; Bös, Fabian; Pleiss, Jürgen (2009). "The Lactamase Engineering Database: a critical survey of TEM sequences in public databases". BMC Genomics. 10 (1): 390. doi:10.1186/1471-2164-10-390. ISSN 1471-2164. PMC 2742552.
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