Lelis syndrome
| Lelis syndrome | |
|---|---|
| Other names | Ectodermal dysplasia-acanthosis nigricans syndrome |
 | |
| This condition is inherited via an autosomal recessive manner | |
Lelis syndrome it is a genetic disorder, a rare condition with dermatological and dental findings[1] characterized by the association of ectodermal dysplasia (hypotrichosis and hypohidrosis) with acanthosis nigricans. Other clinical features may include palmoplantar hyperkeratosis, nail dystrophy, ,[2] disturbances of skin pigmentation (perioral and periorbital hyperpigmentation, vitiligo, and perinevic leukoderma)[2] and hypodontia. Transmission is autosomal recessive.[1][3]
See also[]
- List of cutaneous conditions
References[]
- ^ a b Samdani AJ (October 2004). "Ectodermal dysplasia with acanthosis nigricans (Lelis' syndrome)". . 14 (10): 626–7. doi:10.2004/JCPSP.626627 (inactive 31 October 2021). PMID 15456556.
{{cite journal}}: CS1 maint: DOI inactive as of October 2021 (link) - ^ a b Lelis J (June 1992). "Autosomal recessive ectodermal dysplasia". Cutis. 49 (6): 435–7. PMID 1628512.
- ^ Steiner CE, Cintra ML, Marques-de-Faria AP (December 2002). "Ectodermal dysplasia with acanthosis nigricans (Lelis syndrome)". Am. J. Med. Genet. 113 (4): 381–4. doi:10.1002/ajmg.b.10787. PMID 12457412.
External links[]
Categories:
- Rare syndromes
- Syndromes affecting the skin
- Genodermatoses
- Genetic disorders with OMIM but no gene
- Syndromes affecting teeth
- Genodermatoses stubs