List of unusual biological names
The trouble with unusual names has not been lost on scientists when needing to explain genetic diseases to lay-people.[1] This has particularly been noted in patients with a defect in the sonic hedgehog gene pathway and the disease formerly named CATCH22 for "cardiac anomaly, T-cell deficit, clefting and hypocalcaemia for chromosome 22q11.2 microdeletions". This name was abandoned due to the no-win connotations.[2]
In 1993 Alfonso Martinez Arias, a researcher at the University of Cambridge, was ordered to change the name of the gene he had discovered, VELCRO, because of copyright issues with Velcro.[3] The gene was re-named to puckered.[4] In 2005, Pokémon threatened to sue the discoverer of POKEMON because the name was attracting attention when its link to the development of cancer was published.[3]
Genes and proteins[]
In the early discovery days of genomics, genes were often given creative names upon discovery. Although a nomenclature committee has now been formed, several of these names remain.[5]
Name | Explanation | Biological role |
---|---|---|
Bag-of-marbles | ||
Buttonhead | ||
Cheap date[6] | mutations in this gene cause marked susceptibility to alcohol intoxication | |
Deadpan | ||
DIABLO | Direct IAP binding protein, low | |
Dreadlocks | mutations in this gene cause cell projections to clump together like dreadlocks | murine ortholog of Nck |
Dunce | a memory-related gene | a memory-related gene associated with Rutabaga |
ELMO | Engulfment and Cell Motility | contains the family ELMO1, ELMO2, and ELMO3 |
Exuperantia | named after St. Exuperantia who was beheaded[citation needed] | a gene associated with dividing the head and body into regions |
Fizzy-related | ||
Flippase | a protein that "flips" phosphatidylserines on the inner side of the cell membrane | |
Floppase | a protein that "flops" phosphatidylserines on the outer side of the cell membrane | |
|
named for the video game character Sonic the Hedgehog | critical gene involved in development and tumorigenesis |
Headcase[7] | ||
Hunchback | ||
Indy | short for I'm not dead yet | |
Ken and Barbie[8] | drosophila gene | |
Lunatic Fringe, Manic Fringe, and Radical Fringe | ||
MAP kinase kinase kinase and MAP kinase kinase kinase kinase | ||
Mothers against decapentaplegic 1-9, and the associated [9] | Takes the name from "Mothers against drunk driving" and similar campaigns | Mutations in the gene of the mother cause improper development in the offspring |
NEMO | NF-kappa-B essential modulator | |
Methuselah-like proteins | named for Methuselah, extends the lifespan of an organism | |
RING | short for Really Interesting New Gene | |
POKEMON | POK erythroid myeloid ontogenic factor, changed to Zbtb7 after a lawsuit was threatened[10] | |
Pikachurin | ||
Salvador | ||
Scramblase | an enzyme that "scrambles" phospholipids between the inside and outside of the cell membrane | |
Slingshot homolog | ||
Slit-Robo and the associated | ||
SMURF1 and SMURF2, which interacts with Mothers against decapentaplegic 7 | SMAD Ubiquitination Regulatory Factor 1/2 | |
SPOCK1 | Zebrafish with this mutation develop pointed-ears reminiscent of Spock | |
SWEET transporters | Sugars will eventually be exported | Sugar transporters |
Swiss cheese[11] | mutations cause the brain to develop with lesions resembling Swiss cheese | |
Tafazzin | Named after the masochistic Italian comic character Tafazzi after alleged hardships in its discovery | |
Time for Coffee[12] | Active in the night. | Regulator of circardian clock in Arabidopsis thaliana |
Tinman gene | named for the tinman, required for proper development of the heart |
Molecules[]
- Moronic acid, a natural triterpene
- Traumatic acid, a monounsaturated dicarboxylic acid naturally occurring in plants
Species[]
- Aerodactylus, a disputed pterosaur genus named for the Pokémon Aerodactyl.
- Choeras zygon, a species of parasitoid wasp named after the Zygons from Doctor Who.[13]
- Midichloria, a genus of Gram-negative, non spore-forming bacteria, is derived from the midi-chlorians, a symbiotic, microscopic life form described in the fictional Star Wars universe.[14]
- Spongiforma squarepantsii, a fungus species from Malaysia named after the Nickelodeon character SpongeBob SquarePants from the show of the same name.
- Thanos simonattoi, a species of theropod named after the supervillain Thanos from Marvel Comics.[15]
- Yoda purpurata, a species of acorn worm from the North Atlantic ocean, was named after the fictional character Yoda from the Star Wars franchise.[16][17] It is the only known hermaphroditic member within the phylum.[18]
- Anelosimus dude and Anelosimus biglebowski are closely related species of spiders found only in the Udzungwa Mountains in Tanzania. The former is named after Jeffrey "The Dude" Lebowski, the protagonist of the 1998 film The Big Lebowski, while the latter is named after the film itself. [19]
Techniques[]
- Chromatin Interaction Analysis by Paired-End Tag Sequencing (ChIA-PET) is a technique to determine chromatin interactions which shares a name with Chia Pets.
See also[]
References[]
- ^ Hopkin, Michael (2006). "Troublesome gene names get the boot". News@nature. doi:10.1038/news061106-2. S2CID 86514270.
- ^ MacLean, Ken (2006). "Humour of gene names lost in translation to patients". Nature. 439 (7074): 266. Bibcode:2006Natur.439..266M. doi:10.1038/439266d. PMID 16421543.
- ^ Jump up to: a b Simonite, Tom (2005). "Pokémon blocks gene name". Nature. 438 (7070): 897. Bibcode:2005Natur.438..897S. doi:10.1038/438897a. PMID 16355177.
- ^ "puc puckered [ Drosophila melanogaster (fruit fly) ]".
- ^ https://psmag.com/sonic-hedgehog-dicer-and-the-problem-with-naming-genes-113c58df8f7a[full citation needed]
- ^ Moore, Monica S; Dezazzo, Jim; Luk, Alvin Y; Tully, Tim; Singh, Carol M; Heberlein, Ulrike (1998). "Ethanol Intoxication in Drosophila: Genetic and Pharmacological Evidence for Regulation by the cAMP Signaling Pathway". Cell. 93 (6): 997–1007. doi:10.1016/S0092-8674(00)81205-2. PMID 9635429. S2CID 15312752.
- ^ http://www.sdbonline.org/sites/fly/dbzhnsky/headcse1.htm[full citation needed]
- ^ Lukacsovich, Tamas; Yuge, Kazuya; Awano, Wakae; Asztalos, Zoltan; Kondo, Shunzo; Juni, Naoto; Yamamoto, Daisuke (2003). "Theken and barbie gene encoding a putative transcription factor with a BTB domain and three zinc finger motifs functions in terminalia development of Drosophila". Archives of Insect Biochemistry and Physiology. 54 (2): 77–94. doi:10.1002/arch.10105. PMID 14518006.
- ^ http://flybase.org/reports/FBgn0020493.html[full citation needed]
- ^ Brendan Sinclair (2005-12-19). "Pokémon USA threatens to sue cancer researchers". GameSpot. Retrieved 2016-01-31.
- ^ Kretzschmar, D; Hasan, G; Sharma, S; Heisenberg, M; Benzer, S (1997). "The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila". The Journal of Neuroscience. 17 (19): 7425–32. doi:10.1523/JNEUROSCI.17-19-07425.1997. PMC 6573436. PMID 9295388.
- ^ "TIC - Protein TIME FOR COFFEE - Arabidopsis thaliana (Mouse-ear cress) - TIC gene & protein". www.uniprot.org. Retrieved 2021-03-12.
- ^ "Choeras zygon Fagan-Jeffries & Austin, 2019". GBIF. Retrieved 2020-12-18.
- ^ Sassera, D; Beninati, T; Bandi, C; Bouman, EA; Sacchi, L; Fabbi, M; Lo, N (November 2006). "'Candidatus Midichloria mitochondrii', an endosymbiont of the tick Ixodes ricinus with a unique intramitochondrial lifestyle". International Journal of Systematic and Evolutionary Microbiology. 56 (Pt 11): 2535–40. doi:10.1099/ijs.0.64386-0. PMID 17082386.
- ^ Delcourt, Rafael; Vidoi Iori, Fabiano (2018). "A new Abelisauridae (Dinosauria: Theropoda) from São José do Rio Preto Formation, Upper Cretaceous of Brazil and comments on the Bauru Group fauna". Historical Biology. 32 (7): 917–924. doi:10.1080/08912963.2018.1546700. S2CID 92754354.
- ^ Newly Discovered Acorn Worm Named After Yoda Archived 2013-02-10 at the Wayback Machine, retrieved 2012-10-06 18:05 UTC
- ^ Priede, Imants G.; Osborn, Karen J.; Gebruk, Andrey V.; Jones, Dan; Shale, David; Rogacheva, Antonina; Holland, Nicholas D. (2012). "Observations on torquaratorid acorn worms (Hemichordata, Enteropneusta) from the North Atlantic with descriptions of a new genus and three new species" (PDF). Invertebrate Biology. 131 (3): 244–257. doi:10.1111/j.1744-7410.2012.00266.x. ISSN 1077-8306.
- ^ Priede, Imants G. (2012). "Observations on torquaratorid acorn worms (Hemichordata, Enteropneusta) from the North Atlantic with descriptions of a new genus and three new species" (PDF). Invertebrate Biology. 131 (3): 244–257. doi:10.1111/j.1744-7410.2012.00266.x.
- ^ Agnarsson, Ingi; Zhang, Jun-Xia (2006). "New species of Anelosimus (Araneae: Theridiidae) from Africa and Southeast Asia, with notes on sociality and color polymorphism" (PDF). Zootaxa. 1147: 1–34. doi:10.11646/zootaxa.1147.1.1. Retrieved 22 March 2015.
- Lists of things considered unusual