MAB21L2
MAB21L2 | |||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||
Aliases | MAB21L2, MCOPS14, Mab-21-like 2 (C. elegans), mab-21 like 2, MCSKS14 | ||||||||||||||||||||||||
External IDs | OMIM: 604357 MGI: 1346022 HomoloGene: 7824 GeneCards: MAB21L2 | ||||||||||||||||||||||||
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Orthologs | |||||||||||||||||||||||||
Species | Human | Mouse | |||||||||||||||||||||||
Entrez | |||||||||||||||||||||||||
Ensembl | |||||||||||||||||||||||||
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RefSeq (mRNA) | |||||||||||||||||||||||||
RefSeq (protein) | |||||||||||||||||||||||||
Location (UCSC) | Chr 4: 150.58 – 150.58 Mb | Chr 3: 86.55 – 86.55 Mb | |||||||||||||||||||||||
PubMed search | [3] | [4] | |||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||
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Mab-21-like 2 (C. elegans) is a protein that in humans is encoded by the MAB21L2 gene.[5]
Function[]
This gene is similar to the C. elegans MAB-21 cell fate-determining gene, a downstream target of transforming growth factor-beta signaling. It is thought that this gene may be involved in neural development. The protein encoded by this gene is primarily nuclear, although some cytoplasmic localization has been observed. [provided by RefSeq, Jul 2008].
References[]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000181541 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000057777 - Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Mab-21-like 2 (C. elegans)".
Further reading[]
- Mariani M, Baldessari D, Francisconi S, Viggiano L, Rocchi M, Zappavigna V, Malgaretti N, Consalez GG (December 1999). "Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development". Human Molecular Genetics. 8 (13): 2397–406. doi:10.1093/hmg/8.13.2397. PMID 10556287.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Categories:
- Genes on human chromosome 4
- Human chromosome 4 gene stubs