Martin D. Burke

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Martin D. Burke
Born (1976-02-05) February 5, 1976 (age 45)
Westminster, Maryland
Alma materHarvard University Ph.D. (2003), M.D. (2005)
Johns Hopkins University B.A. (1998)
AwardsBeckman Young Investigators Award[1]
Nobel Laureate Signature Award[2]
Scientific career
FieldsOrganic Chemistry
InstitutionsUniversity of Illinois at Urbana–Champaign
ThesisA synthesis strategy for generating diverse skeletons of small molecules combinatorially (2004)
Doctoral advisorStuart L. Schreiber
Other academic advisorsHenry Brem and Gary H. Posner
Websitewww.chemistry.illinois.edu/faculty/Martin_Burke.html

Martin D. Burke (born February 5, 1976 in Westminster, Maryland) is the May and Ving Lee Professor for Chemical Innovation at the University of Illinois at Urbana–Champaign,[3] and Associate Dean of Research in the Carle Illinois College of Medicine.[4] His research has involved the development of antifungal treatments for cystic fibrosis,[5] and the development of a COVID-19 test that the University of Illinois has used over one million times.[6]

Early life and education[]

Burke was born on February 5, 1976 in Westminster, Maryland.[4] Burke studied chemistry as an undergraduate at Johns Hopkins University, graduating in 1998 with his B.A. in Chemistry. While an undergraduate, he was a Howard Hughes Medical Institute Undergraduate Research Fellow, and he conducted research with Professors Henry Brem and Gary H. Posner on derivatives of calcitriol as potential drug candidates.[7][8] Burke went on to Harvard University, where he earned a Ph.D. and M.D. in 2003 and 2005, respectively. Burke conducted his Ph.D. thesis work with Professor Stuart L. Schreiber on the combinatorial synthesis of small molecules with diverse skeletons.[9][10][11]

Independent career[]

He joined the Department of Chemistry in 2005 as an Assistant Professor, was promoted to Associate Professor in 2011, then to full Professor in 2014. He was appointed Associate Dean of Research of the Carle-Illinois College of Medicine in 2018.[4][12]

Recognition[]

Burke was named a Beckman Foundation Young Investigator in 2008.[1][4] In 2013 the American Chemical Society gave him their Elias J. Corey Award for Outstanding Original Contribution in Organic Synthesis by a Young Investigator,[4] and in 2017 they named Burke their Nobel Laureate Signature Award in Graduate Education in Chemistry.[2][4]

References[]

  1. ^ a b "Martin D. Burke". Arnold and Mabel Beckman Foundation. Retrieved 9 March 2017.
  2. ^ a b https://www.acs.org/content/acs/en/funding-and-awards/awards/national/bytopic/nobel-laureate-signature-award-for-graduate-education-in-chemistry.html
  3. ^ "Chemistry faculty". University of Illinois at Urbana–Champaign. Retrieved 2020-12-17.
  4. ^ a b c d e f "Curriculum vitae" (PDF). University of Illinois at Urbana–Champaign. Retrieved 2020-12-17.
  5. ^ Service, Robert (March 2019). "Antifungal drug could help cystic fibrosis patients for whom common treatments don't work". Science. doi:10.1126/science.aax3254.
  6. ^ "University of Illinois System completes 1 million COVID-19 tests". WAND TV. December 4, 2020.
  7. ^ Posner, Gary H.; Lee, Jae Kyoo; Wang, Qiang; Peleg, Sara; Burke, Martin; Brem, Henry; Dolan, Patrick; Kensler, Thomas W. (1998). "Noncalcemic, Antiproliferative, Transcriptionally Active, 24-Fluorinated Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D3. Synthesis and Preliminary Biological Evaluation". Journal of Medicinal Chemistry. 41 (16): 3008–3014. doi:10.1021/jm980031t. ISSN 0022-2623. PMID 9685240.
  8. ^ White, M.Christina; Burke, Martin D.; Peleg, Sara; Brem, Henry; Posner, Gary H. (2001-07-01). "Conformationally Restricted Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D3: Design, Synthesis, and Biological Evaluation". Bioorganic & Medicinal Chemistry. 9 (7): 1691–1699. doi:10.1016/S0968-0896(01)00087-6. ISSN 0968-0896. PMID 11425569.
  9. ^ Kirkpatrick, Peter (2003). "New directions in chemical space". Nature Reviews Drug Discovery. 2 (12): 948. doi:10.1038/nrd1266. ISSN 1474-1784.
  10. ^ Burke, Martin D.; Berger, Eric M.; Schreiber, Stuart L. (2003-10-24). "Generating Diverse Skeletons of Small Molecules Combinatorially". Science. 302 (5645): 613–618. Bibcode:2003Sci...302..613B. doi:10.1126/science.1089946. ISSN 0036-8075. PMID 14576427. S2CID 6168881.
  11. ^ Burke, Martin D.; Berger, Eric M.; Schreiber, Stuart L. (2004). "A Synthesis Strategy Yielding Skeletally Diverse Small Molecules Combinatorially". Journal of the American Chemical Society. 126 (43): 14095–14104. doi:10.1021/ja0457415. ISSN 0002-7863. PMID 15506774.
  12. ^ "University of Illinois Board of Trustees, Promotions recommended to be effective at the beginning of the 2014-15 academic year" (PDF).

External links[]

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