NFRKB

NFRKB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3U21, 4UF6, 4WLP
Identifiers
Aliases	NFRKB, INO80G, nuclear factor related to kappaB binding protein
External IDs	OMIM: 164013 MGI: 2442410 HomoloGene: 4492 GeneCards: NFRKB
Gene location (Human)
Chr.	Chromosome 11 (human)
End	129,895,590 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	31,332,629 bp
RNA expression pattern
	Top expressed in
	ovary; ; testicle; ; vagina; ; kidney; ; lung;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protease binding; DNA binding; GO:0001948 protein binding;
Cellular component	nucleus; Ino80 complex; nucleoplasm;
Biological process	DNA recombination; inflammatory response; regulation of transcription, DNA-templated; transcription by RNA polymerase II; DNA repair; transcription, DNA-templated; cellular response to DNA damage stimulus; protein deubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	4798
	235134
	ENSG00000170322
	ENSMUSG00000042185
	Q6P4R8
	Q6PIJ4
	NM_001143835; NM_006165
	NM_172766; NM_001359654
	NP_001137307; NP_006156; NP_001137307.1
	NP_766354; NP_001346583
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear factor related to kappa-B-binding protein is a protein that in humans is encoded by the NFRKB gene.^[5]^[6]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170322 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042185 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Adams BS, Leung K, Meltzer PS, Lewis KA, Wagner-McPherson C, Evans GA, Nabel GJ (Dec 1992). "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25" (PDF). Genomics. 14 (2): 270–4. doi:10.1016/S0888-7543(05)80216-2. hdl:2027.42/29810. PMID 1427843.
^ "Entrez Gene: NFRKB nuclear factor related to kappaB binding protein".

Further reading[]

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Urban MB, Schreck R, Baeuerle PA (1991). "NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit". EMBO J. 10 (7): 1817–25. doi:10.1002/j.1460-2075.1991.tb07707.x. PMC 452856. PMID 2050119.
Adams BS, Leung KY, Hanley EW, Nabel GJ (1992). "Cloning of R kappa B, a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site". New Biol. 3 (11): 1063–73. PMID 1777480.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by .

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170322 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042185 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1427843-5] Adams BS, Leung K, Meltzer PS, Lewis KA, Wagner-McPherson C, Evans GA, Nabel GJ (Dec 1992). "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25" (PDF). Genomics. 14 (2): 270–4. doi:10.1016/S0888-7543(05)80216-2. hdl:2027.42/29810. PMID 1427843.

[entrez-6] "Entrez Gene: NFRKB nuclear factor related to kappaB binding protein".

[1]

[2]

[3]

[4]

[5]

[6]