NOTUM (gene)

NOTUM
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UYU, 4UYW, 4UYZ, 4UZ1, 4UZ5, 4UZ6, 4UZ7, 4UZ9, 4UZA, 4UZL, 4UZQ, 4WBH
Identifiers
Aliases	NOTUM, hpalmitoleoyl-protein carboxylesterase
External IDs	OMIM: 609847 MGI: 1924833 HomoloGene: 45335 GeneCards: NOTUM
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,961,840 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	120,552,001 bp
RNA expression pattern
	Top expressed in
	quadriceps femoris muscle; ; liver; ; pancreas; ; Right lobe of liver; ; testicle; ; bone marrow;
	More reference expression data
	n/a
Gene ontology
Molecular function	palmitoleyl hydrolase activity; GO:0004091 carboxylic ester hydrolase activity; hydrolase activity; phospholipase C activity;
Cellular component	extracellular region; endoplasmic reticulum lumen;
Biological process	negative regulation of Wnt signaling pathway; protein depalmitoleylation; Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; post-translational protein modification; cellular protein metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	147111
	77583
	ENSG00000185269
	ENSMUSG00000042988
	Q6P988
	Q8R116
	NM_178493
	NM_175263; NM_001382269; NM_001382270
	NP_848588
	NP_780472; NP_001369198; NP_001369199
	Wikidata
View/Edit Human	View/Edit Mouse

Notum, palmitoleoyl-protein carboxylesterase is a protein that in humans is encoded by the NOTUM gene. ^[5]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185269 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042988 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Notum, palmitoleoyl-protein carboxylesterase". Retrieved 2018-06-15.

PDBe-KB provides an overview of all the structure information available in the PDB for Human Palmitoleoyl-protein carboxylesterase NOTUM

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