NSMCE4A

NSMCE4A
Identifiers
Aliases	NSMCE4A, C10orf86, NS4EA, NSE4A, NSE4 homolog A, SMC5-SMC6 complex component
External IDs	OMIM: 612987 MGI: 1915122 HomoloGene: 9745 GeneCards: NSMCE4A
Gene location (Human)
Chr.	Chromosome 10 (human)
End	121,975,217 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	130,174,848 bp
RNA expression pattern
	Top expressed in
	Body of pancreas; ; esophagus; ; gastric mucosa; ; fundus; ; prostate;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	GO:0001948 protein binding;
Cellular component	chromosome, telomeric region; Smc5-Smc6 complex; nucleus; chromosome; nucleoplasm; nuclear body;
Biological process	DNA recombination; DNA repair; positive regulation of response to DNA damage stimulus; cellular response to DNA damage stimulus;
	Sources:Amigo / QuickGO
Orthologs
	54780
	67872
	ENSG00000107672
	ENSMUSG00000040331
	Q9NXX6
	n/a
	NM_001167865; NM_017615
	NM_001162855
	NP_001161337; NP_060085
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene.^[5]^[6]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000107672 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040331 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hu B, Liao C, Millson SH, Mollapour M, Prodromou C, Pearl LH, Piper PW, Panaretou B (Mar 2005). "Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex". Mol Microbiol. 55 (6): 1735–50. doi:10.1111/j.1365-2958.2005.04531.x. PMID 15752197. S2CID 40645007.
^ "Entrez Gene: NSMCE4A non-SMC element 4 homolog A (S. cerevisiae)".

Further reading[]

Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by .

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000107672 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040331 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15752197-5] Hu B, Liao C, Millson SH, Mollapour M, Prodromou C, Pearl LH, Piper PW, Panaretou B (Mar 2005). "Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex". Mol Microbiol. 55 (6): 1735–50. doi:10.1111/j.1365-2958.2005.04531.x. PMID 15752197. S2CID 40645007.

[entrez-6] "Entrez Gene: NSMCE4A non-SMC element 4 homolog A (S. cerevisiae)".

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