Nicotine polacrilex

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Nicotine polacrilex is nicotine bound to an ion-exchange resin (polymethacrylic acid, such as Amberlite IRP64, Purolite C115HMR or Doshion P551). It is added to gums and hard lozenges used for nicotine replacement therapy in smoking cessation. The use of the polymer as a delivery system maximizes the amount of nicotine released and absorbed by the oral mucosa. 80 to 90 percent of the nicotine released from the gum is absorbed by the mouth. Side effects of the gum include bad taste, nausea, dyspepsia, and stomatitis.

See also[]

• Nicotine gum

References[]

External links[]

• "Nicotine polacrilex". Drug Information Portal. U.S. National Library of Medicine.
• Nicotine polacrilex at the US National Library of Medicine Medical Subject Headings (MeSH)

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