Non-cirrhotic portal fibrosis
| Non-cirrhotic portal fibrosis | |
|---|---|
 | |
| Non-cirrhotic portal fibrosis is inherited in an autosomal recessive manner |
Non-cirrhotic portal fibrosis (NCPF) is a chronic liver disease[1] and type of non-cirrhotic portal hypertension (NCPH).
Presentation[]
It is characterized by 'obliterative portovenopathy', which leads to various problems such as portal hypertension, massive splenomegaly, and variceal bleeding. It is estimated that about 85% of people with NCPF have repeated episodes of variceal bleeding.[2]
Diagnosis[]
Hallmark of the disease is thrombosis/sclerosis of branches of portal vein. Vessels formed are often termed as mesangiosinusoids or periportal cavernoma.
Liver transplantation
References[]
- ^ Nayak, NC; Jain, D; Saigal, S; Soin, AS (July 2011). "Non-cirrhotic portal fibrosis: one disease with many names? An analysis from morphological study of native explant livers with end stage chronic liver disease". Journal of Clinical Pathology. 64 (7): 592–8. doi:10.1136/jcp.2010.087395. PMID 21685145.
- ^ Sarin, SK (December 2002). "Non-cirrhotic portal fibrosis". Journal of Gastroenterology and Hepatology. 17 Suppl 3: S214-23. doi:10.1046/j.1440-1746.17.s3.3.x. PMC 1378468. PMID 12472939.
External links[]
 | This article about a disease, disorder, or medical condition is a stub. You can help Wikipedia by . |
Categories:
- Diseases of liver
- Disease stubs