Norpsilocin
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Names | |
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IUPAC name
3-[2-(methylamino)ethyl]-1H-indol-4-ol
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Other names
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Identifiers | |
3D model (JSmol)
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PubChem CID
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Properties | |
C11H14N2 | |
Molar mass | 174.247 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Norpsilocin or 4-HO-NMT is naturally occurring tryptamine alkaloid recently discovered in 2017 in one species called Psilocybe cubensis.[1][2] It is said to be dephosphorylated metabolite of baeocystin however this hypothesis haven't been formally proven.[2] Norpsiloin was found to be a full agonist of 5-HT2A receptor. It is also more potent than psilocin.[3][4]
See also[]
References[]
- ^ Lenz C, Wick J, Hoffmeister D (October 2017). "Identification of ω-N-Methyl-4-hydroxytryptamine (Norpsilocin) as a Psilocybe Natural Product". Journal of Natural Products. 80 (10): 2835–2838. doi:10.1021/acs.jnatprod.7b00407. PMID 28929753.
- ^ a b "Two New Crystalline Forms of Norpsilocin".
- ^ "Study Finds Norpsilocin is More Potent Than Psilocin at 5-HT2A".
- ^ Sherwood AM, Halberstadt AL, Klein AK, McCorvy JD, Kaylo KW, Kargbo RB, Meisenheimer P (February 2020). "Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin". Journal of Natural Products. 83 (2): 461–467. doi:10.1021/acs.jnatprod.9b01061. PMID 32077284.
Categories:
- Indole alkaloids
- Alkaloid stubs