OTUD1

OTUD1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4BOP
Identifiers
Aliases	OTUD1, DUBA7, OTDC1, OTU deubiquitinase 1
External IDs	OMIM: 612022 MGI: 1918448 HomoloGene: 45953 GeneCards: OTUD1
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10p12.2 Start 23,439,075 bp[1] End 23,442,377 bp[1]
RNA expression pattern Bgee Top expressed in synovial membrane gastrocnemius muscle quadriceps femoris muscle ovary prosencephalon testicle deltoid muscle More reference expression data BioGPS n/a
Orthologs
Species	Human	Mouse
Entrez	220213	71198
Ensembl	ENSG00000165312	ENSMUSG00000043415
UniProt	Q5VV17	Q9CUB6
RefSeq (mRNA)	NM_001145373	NM_027715
RefSeq (protein)	NP_001138845	NP_081991
Location (UCSC)	Chr 10: 23.44 – 23.44 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

OTU deubiquitinase 1 is a protein that in humans is encoded by the OTUD1 gene. ^[4]

Function[]

Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.

References[]

External links[]

• PDBe-KB provides an overview of all the structure information available in the PDB for Human OTU domain-containing protein 1

Further reading[]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by .

• v
• t