PPP1R7

PPP1R7
Identifiers
Aliases	PPP1R7, SDS22, protein phosphatase 1 regulatory subunit 7
External IDs	OMIM: 602877 MGI: 1913635 HomoloGene: 2032 GeneCards: PPP1R7
Gene location (Human)
Chr.	Chromosome 2 (human)
End	241,183,652 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	93,301,211 bp
RNA expression pattern
	Top expressed in
	testicle; ; caudate nucleus; ; nucleus accumbens; ; putamen;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	GO:0010576 enzyme regulator activity; GO:0001948 protein binding; protein phosphatase regulator activity;
Cellular component	cytoplasm; extracellular exosome; nucleus; chromosome;
Biological process	positive regulation of protein dephosphorylation; chromosome segregation; GO:0048552 regulation of catalytic activity; regulation of phosphoprotein phosphatase activity; calcium activated phospholipid scrambling;
	Sources:Amigo / QuickGO
Orthologs
	5510
	66385
	ENSG00000115685
	ENSMUSG00000026275
	Q15435
	Q3UM45
NM_001282409; NM_001282410; NM_001282411; NM_001282412; NM_001282413;
	NM_001282414; NM_002712
	NM_023200
NP_001269338; NP_001269339; NP_001269340; NP_001269341; NP_001269342;
	NP_001269343; NP_002703
	NP_075689
	Wikidata
View/Edit Human	View/Edit Mouse

Protein phosphatase 1 regulatory subunit 7 is an enzyme that in humans is encoded by the PPP1R7 gene.^[5]^[6]^[7]^[8]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000115685 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026275 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Renouf S, Beullens M, Wera S, Van Eynde A, Sikela J, Stalmans W, Bollen M (Jan 1996). "Molecular cloning of a human polypeptide related to yeast sds22, a regulator of protein phosphatase-1". FEBS Lett. 375 (1–2): 75–8. doi:10.1016/0014-5793(95)01180-M. PMID 7498485. S2CID 41223011.
^ Berry R, Stevens TJ, Walter NA, Wilcox AS, Rubano T, Hopkins JA, Weber J, Goold R, Soares MB, Sikela JM (Oct 1995). "Gene-based sequence-tagged-sites (STSs) as the basis for a human gene map". Nat Genet. 10 (4): 415–23. doi:10.1038/ng0895-415. PMID 7670491. S2CID 22277955.
^ Ceulemans H, Van Eynde A, Perez-Callejon E, Beullens M, Stalmans W, Bollen M (Jun 1999). "Structure and splice products of the human gene encoding sds22, a putative mitotic regulator of protein phosphatase-1". Eur J Biochem. 262 (1): 36–42. doi:10.1046/j.1432-1327.1999.00344.x. PMID 10231361.
^ "Entrez Gene: PPP1R7 protein phosphatase 1, regulatory (inhibitor) subunit 7".

Lesage B, Beullens M, Pedelini L, et al. (2007). "A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3". Biochemistry. 46 (31): 8909–19. doi:10.1021/bi7003119. PMID 17630778.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ceulemans H, Vulsteke V, De Maeyer M, et al. (2003). "Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1". J. Biol. Chem. 277 (49): 47331–7. doi:10.1074/jbc.M206838200. PMID 12226088.

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