Peter Wipf

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Peter Wipf is the Distinguished University Professor of Chemistry at the University of Pittsburgh. His research interests focus on the discovery of new pharmaceuticals.[1][2] He is a Fellow of three learned societies.

Education[]

Career[]

Dr. Wipf joined the University of Pittsburgh Department of Chemistry in 1990, and has remained there ever since. He became a full professor in 1997, and became a Distinguished University Professor of Chemistry[4] in 2004. In 2001, he was appointed Professor of Pharmaceutical Sciences in the School of Pharmacy. He is director of the university's Center for Chemical Methodologies & Library Development. He has been an Adjunct Professor at Duke University's Department of Chemistry since 2002.[3][5]

His research interests center on the discovery of new drugs,[1] including the total synthesis of natural products, organometallic and heterocyclic chemistry, and medicinal chemistry.[2] He serves on many advisory and editorial boards in the fields of chemistry and pharmaceuticals.

Publications[]

Peter Wipf is the author or coauthor of over 500 academic publications.[6] Seventy-five of his original research publications have been cited over 100 times in the literature, including:[3]

  • Wipf, P.; Miller, C. P., "A new synthesis of highly functionalized oxazoles." J. Org. Chem. 1993, 58, 3604.
  • Wipf, P.; Cunningham, A., "A solid phase protocol of the Biginelli dihydropyrimidine Synthesis suitable for combinatorial chemistry." Tetrahedron Lett. 1995, 36, 7819.
  • Wipf, P.; Lim, S., "Total synthesis of the enantiomer of the antiviral marine natural product hennoxazole A." J. Am. Chem. Soc. 1995, 117, 558.
  • Wipf, P.; Kim, Y.; Goldstein, D. M., "Asymmetric total synthesis of the Stemona alkaloid (-)-stenine." J. Am. Chem. Soc. 1995, 117, 11106.
  • Studer, A.; Jeger, P.; Wipf, P.; Curran, D. P., "Fluorous synthesis: Fluorous protocols for the Biginelli and Ugi multi-component condensations." J. Org. Chem. 1997, 62, 2917.
  • Wipf, P.; Ribe, S., "Zirconocene-zinc transmetalation and in situ catalytic asymmetric addition to aldehydes." J. Org. Chem. 1998, 63, 6454.
  • Kondru, R. K.; Wipf, P.; Beratan, D. N., "Atomic contributions to the optical rotation angle as a quantitative probe of molecular chirality." Science 1998, 282, 2247.
  • Phillips, A. J.; Uto, Y.; Wipf, P.; Reno, M. J.; Williams, D. R., "Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor." Org. Lett. 2000, 2, 1165.
  • Lazo, J. S.; Aslan, D. C.; Southwick, E. C.; Cooley, K. A.; Ducruet, A. P.; Joo, B.; Vogt, A.; Wipf, P., "Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25." J. Med. Chem. 2001, 44, 4042.
  • Ihle, N. T.; Williams, R.; Chow, S.; Chew, W.; Berggren, M. I.; Paine-Murrieta, G.; Minion, D. J.; Halter, R. J.; Wipf, P.; Abraham, R.; Kirkpatrick, L.; Powis, G., "Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling." Mol. Cancer Therap. 2004, 3, 763.

Honors and awards[]

Among many other honors and awards, Dr. Wipf is a:[2]

References[]

  1. ^ a b "Peter Wipf, PhD". University of Pittsburgh Department of Pharmacology and Chemical Biology website. University of Pittsburgh. Archived from the original on 2019-02-02. Retrieved 2017-03-10.
  2. ^ a b c "Peter Wipf / Department of Chemistry". University of Pittsburgh Department of Chemistry website. University of Pittsburgh. Archived from the original on 2017-03-12. Retrieved 2017-03-10.
  3. ^ a b c d e "Peter Wipf, PhD Biographical Sketch" (PDF). University of Pittsburgh Department of Chemistry website. University of Pittsburgh. Retrieved 2017-03-10.
  4. ^ "Policy and Procedure Governing Appointments to Distinguished Professorships". University of Pittsburgh Faculty Handbook. University of Pittsburgh. 2013-02-05. Archived from the original on 2007-09-05. Retrieved 2017-03-16.
  5. ^ "Peter Wipf Wins Morley Medal". Chemical & Engineering News. American Chemical Society. 2013-07-22. Archived from the original on 2017-03-12. Retrieved 2017-03-10.
  6. ^ ""Wipf P"[au]". PubMed.gov. US National Library of Medicine, National Institutes of Health. Archived from the original on 2017-03-14. Retrieved 2017-03-10.
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