Phenyl phosphorodiamidate
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Names | |
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Preferred IUPAC name
Phenyl phosphorodiamidate | |
Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.028.380 ![]() |
EC Number |
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C6H9N2OP | |
Molar mass | 156.125 g·mol−1 |
Appearance | white solid |
Melting point | 185 °C (365 °F; 458 K) |
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GHS labelling: | |
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Signal word
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Warning |
H302, H319 | |
P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Phenyl phosphorodiamidate is an organophosphorus compound with the formula C6H5OP(O)(NH2)2. A white solid, it is used as an inhibitor of urease,[1] an enzyme that accelerates the hydrolysis of urea. In this way, phenyl phosphorodiamidate enhances the effectiveness of urea-based fertilizers. It is a component of the technology of controlled release fertilizers.[2]
In terms of its molecular structure, phenyl phosphorodiamidate is a tetrahedral molecule structurally related to urea, hence its inhibitory function. It is a derivative of phosphoryl chloride.
See also[]
- N-(n-butyl)thiophosphoric triamide, a related urease inhibitor
References[]
- ^ Gholivand, Khodayar; Pooyan, Mahsa; Mohammadpanah, Fahimeh; Pirastefar, Foroogh; Junk, Peter C.; Wang, Jun; Ebrahimi Valmoozi, Ali Asghar; Mani-Varnosfaderani, Ahmad (2019). "Synthesis, Crystal Structure and Biological Evaluation of New Phosphoramide Derivatives as Urease Inhibitors Using Docking, QSAR and Kinetic Studies". Bioorganic Chemistry. 86: 482–493. doi:10.1016/j.bioorg.2019.01.064. PMID 30772649.
- ^ Pan, Baobao; Lam, Shu Kee; Mosier, Arvin; Luo, Yiqi; Chen, Deli (2016). "Ammonia Volatilization from Synthetic Fertilizers and its Mitigation Strategies: A Global Synthesis". Agriculture, Ecosystems & Environment. 232: 283–289. doi:10.1016/j.agee.2016.08.019.
Categories:
- Phosphoramides
- Soil improvers
- Fertilizers