PyrR binding site
PyrR binding site | |
---|---|
![]() Predicted secondary structure and sequence conservation of PyrR | |
Identifiers | |
Symbol | PyrR |
Rfam | RF00515 |
Other data | |
RNA type | Cis-reg |
Domain(s) | Bacteria |
SO | SO:0000233 |
PDB structures | PDBe |
The PyrR binding site is an RNA element that is found upstream of a variety of genes involved in pyrimidine biosynthesis and transport.[1]
The RNA structure permits binding of PyrR protein which regulates pyrimidine biosynthesis in Bacillus subtilis. When the protein binds, a downstream terminator hairpin forms, repressing transcription of biosynthesis genes.[1]
References[]
- ^ a b Bonner ER, D'Elia JN, Billips BK, Switzer RL (December 2001). "Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR". Nucleic Acids Research. 29 (23): 4851–4865. doi:10.1093/nar/29.23.4851. PMC 96680. PMID 11726695.
External links[]
Categories:
- Cis-regulatory RNA elements
- Molecular and cellular biology stubs