RAB21

RAB21
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1YZT, 1YZU, 1Z08, 1Z0I, 2OT3
Identifiers
Aliases	RAB21, member RAS oncogene family
External IDs	OMIM: 612398 MGI: 894308 HomoloGene: 8991 GeneCards: RAB21
Gene location (Human)
Chr.	Chromosome 12 (human)
End	71,800,286 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	115,151,499 bp
RNA expression pattern
	Top expressed in
	left coronary artery; ; heart; ; ovary; ; internal globus pallidus; ; left ventricle; ; right ventricle; ; testicle; ; corpus callosum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GDP binding; GTP binding; GO:0001948 protein binding; GO:0006184 GTPase activity;
Cellular component	endosome; Golgi apparatus; endoplasmic reticulum membrane; membrane; focal adhesion; vesicle membrane; Golgi membrane; Golgi cisterna membrane; trans-Golgi network; endoplasmic reticulum; neuron projection; cytoplasmic side of plasma membrane; cytoplasmic side of early endosome membrane; cleavage furrow; extracellular exosome; cytoplasmic vesicle membrane; GO:0016023 cytoplasmic vesicle; axon cytoplasm; cytosol; early endosome membrane; early endosome; synapse;
Biological process	positive regulation of receptor-mediated endocytosis; regulation of axon extension; anterograde axonal transport; regulation of exocytosis; positive regulation of dendrite morphogenesis; protein transport; positive regulation of early endosome to late endosome transport; transport; intracellular protein transport; Rab protein signal transduction; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	23011
	216344
	ENSG00000080371
	ENSMUSG00000020132
	Q9UL25
	P35282
	NM_014999
	NM_024454
	NP_055814
	NP_077774
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-21 is a protein that in humans is encoded by the RAB21 gene.^[5]^[6]^[7]^[8]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000080371 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020132 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Opdam FJ, Kamps G, Croes H, van Bokhoven H, Ginsel LA, Fransen JA (Oct 2000). "Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells". Eur J Cell Biol. 79 (5): 308–16. doi:10.1078/S0171-9335(04)70034-5. PMID 10887961.
^ Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
^ Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J (Jun 2006). "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins". J Cell Biol. 173 (5): 767–80. doi:10.1083/jcb.200509019. PMC 2063892. PMID 16754960.
^ "Entrez Gene: RAB21 RAB21, member RAS oncogene family".