RAB35

RAB35
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3TW8
Identifiers
Aliases	RAB35, H-ray, RAB1C, RAY, member RAS oncogene family
External IDs	OMIM: 604199 MGI: 1924657 HomoloGene: 21361 GeneCards: RAB35
Gene location (Human)
Chr.	Chromosome 12 (human)
End	120,117,502 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	115,785,795 bp
RNA expression pattern
	Top expressed in
	blood; ; prefrontal cortex; ; spleen; ; urinary bladder;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GDP binding; GTP binding; GO:0001948 protein binding; phosphatidylinositol-4,5-bisphosphate binding; GO:0006184 GTPase activity;
Cellular component	endosome; membrane; melanosome; clathrin-coated endocytic vesicle; plasma membrane; mitochondrion; cell projection membrane; intercellular bridge; clathrin-coated pit; endosome membrane; extracellular exosome; GO:0016023 cytoplasmic vesicle; clathrin-coated vesicle; cytosol; clathrin-coated vesicle membrane; recycling endosome membrane; anchored component of synaptic vesicle membrane; Golgi membrane; intracellular anatomical structure;
Biological process	protein localization; cellular response to nerve growth factor stimulus; antigen processing and presentation; cytokinesis; endosomal transport; plasma membrane to endosome transport; endocytic recycling; protein transport; protein localization to endosome; neuron projection development; transport; mitotic cytokinesis; intracellular protein transport; Rab protein signal transduction; small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	11021
	77407
	ENSG00000111737
	ENSMUSG00000029518
	Q15286
	Q6PHN9
	NM_001167606; NM_006861
	NM_198163
	NP_001161078; NP_006852
	NP_937806
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-35 is a protein that in humans is encoded by the RAB35 gene.^[5] This GTPase participates in the traffic of recycling endosomes toward the plasma membrane,^[6]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111737 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029518 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: RAB35 RAB35, member RAS oncogene family".
^ Kouranti I, Sachse M, Arouche N, Goud B, Echard A (Sep 2006). "Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis". Current Biology. 16 (17): 1719–25. doi:10.1016/j.cub.2006.07.020. PMID 16950109. S2CID 17407979.

Further reading[]

Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF (Nov 2006). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes". Journal of Proteome Research. 5 (11): 3135–44. doi:10.1021/pr060363j. PMID 17081065.
Kouranti I, Sachse M, Arouche N, Goud B, Echard A (Sep 2006). "Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis". Current Biology. 16 (17): 1719–25. doi:10.1016/j.cub.2006.07.020. PMID 16950109. S2CID 17407979.
Abe Y, Takeuchi T, Imai Y, Murase R, Kamei Y, Fujibuchi T, Matsumoto S, Ueda N, Ogasawara M, Shigemoto K, Kito K (May 2006). "A Small Ras-like protein Ray/Rab1c modulates the p53-regulating activity of PRPK". Biochemical and Biophysical Research Communications. 344 (1): 377–85. doi:10.1016/j.bbrc.2006.03.071. PMID 16600182.
Zhu AX, Zhao Y, Flier JS (Dec 1994). "Molecular cloning of two small GTP-binding proteins from human skeletal muscle". Biochemical and Biophysical Research Communications. 205 (3): 1875–82. doi:10.1006/bbrc.1994.2889. PMID 7811277.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by .

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000111737 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029518 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: RAB35 RAB35, member RAS oncogene family".

[pmid16950109-6] Kouranti I, Sachse M, Arouche N, Goud B, Echard A (Sep 2006). "Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis". Current Biology. 16 (17): 1719–25. doi:10.1016/j.cub.2006.07.020. PMID 16950109. S2CID 17407979.

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