RBM6

RBM6
Identifiers
Aliases	RBM6, 3G2, DEF-3, DEF3, HLC-11, NY-LU-12, g16, RNA binding motif protein 6
External IDs	OMIM: 606886 MGI: 1338037 HomoloGene: 31336 GeneCards: RBM6
Gene location (Human)
Chr.	Chromosome 3 (human)
End	50,100,045 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	107,750,436 bp
RNA expression pattern
	Top expressed in
	fundus; ; prostate; ; Body of pancreas;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; GO:0001948 protein binding; nucleic acid binding; RNA binding;
Cellular component	nucleus;
Biological process	RNA processing;
	Sources:Amigo / QuickGO
Orthologs
	10180
	19654
	ENSG00000004534
	ENSMUSG00000032582
	P78332
	n/a
NM_001167582; NM_005777; NM_001349190; NM_001349191; NM_001349192;
	NM_001349193; NM_001349194
	NM_011251; NM_029169
NP_001161054; NP_005768; NP_001336119; NP_001336120; NP_001336121;
	NP_001336122; NP_001336123
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

RNA-binding protein 6 is a protein that in humans is encoded by the RBM6 gene.^[5]^[6] RBM6 orthologs^[7] have been identified in all mammals for which complete genome data are available.

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000004534 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032582 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Timmer T, Terpstra P, van den Berg A, Veldhuis PM, Ter Elst A, Voutsinas G, Hulsbeek MM, Draaijers TG, Looman MW, Kok K, Naylor SL, Buys CH (Aug 1999). "A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3". Eur J Hum Genet. 7 (4): 478–86. doi:10.1038/sj.ejhg.5200334. PMID 10352938.
^ "Entrez Gene: RBM6 RNA binding motif protein 6".
^ "OrthoMaM phylogenetic marker: RBM6 coding sequence".

Further reading[]

Güre AO, Altorki NK, Stockert E, et al. (1998). "Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3". Cancer Res. 58 (5): 1034–41. PMID 9500467.
Drabkin HA, West JD, Hotfilder M, et al. (1999). "DEF-3(g16/NY-LU-12), an RNA binding protein from the 3p21.3 homozygous deletion region in SCLC". Oncogene. 18 (16): 2589–97. doi:10.1038/sj.onc.1202601. PMID 10353602.
Timmer T, Terpstra P, van den Berg A, et al. (1999). "An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers". Genomics. 60 (2): 238–40. doi:10.1006/geno.1999.5878. PMID 10486216.
Lerman MI, Minna JD (2000). "The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium". Cancer Res. 60 (21): 6116–33. PMID 11085536.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Gu TL, Mercher T, Tyner JW, et al. (2007). "A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia". Blood. 110 (1): 323–33. doi:10.1182/blood-2006-10-052282. PMC 1896120. PMID 17360941.
Wang K, Ubriaco G, Sutherland LC (2007). "RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours". BMC Genomics. 8: 348. doi:10.1186/1471-2164-8-348. PMC 2174484. PMID 17908320.

External links[]

RBM6 human gene location in the UCSC Genome Browser.
RBM6 human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by .

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000004534 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032582 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10352938-5] Timmer T, Terpstra P, van den Berg A, Veldhuis PM, Ter Elst A, Voutsinas G, Hulsbeek MM, Draaijers TG, Looman MW, Kok K, Naylor SL, Buys CH (Aug 1999). "A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3". Eur J Hum Genet. 7 (4): 478–86. doi:10.1038/sj.ejhg.5200334. PMID 10352938.

[entrez-6] "Entrez Gene: RBM6 RNA binding motif protein 6".

[OrthoMaM-7] "OrthoMaM phylogenetic marker: RBM6 coding sequence".

[1]

[2]

[3]

[4]

[5]

[6]

[7]