RHOBTB1

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RHOBTB1
Identifiers
AliasesRHOBTB1, Rho related BTB domain containing 1
External IDsOMIM: 607351 MGI: 1916538 HomoloGene: 8892 GeneCards: RHOBTB1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001081347
NM_001252636
NM_001252637
NM_001252638

RefSeq (protein)

NP_001074816
NP_001239565
NP_001239566
NP_001239567

Location (UCSC)Chr 10: 60.87 – 61 MbChr 10: 68.99 – 69.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Rho-related BTB domain-containing protein 1 is a protein that in humans is encoded by the RHOBTB1 gene.[5][6]

The protein encoded by this gene belongs to the Rho family of the Ras superfamily of small GTPases. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate transcriptional splice variants have been characterized.[6]

References[]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000072422 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019944 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Rivero F, Dislich H, Glockner G, Noegel AA (Mar 2001). "The Dictyostelium discoideum family of Rho-related proteins". Nucleic Acids Res. 29 (5): 1068–79. doi:10.1093/nar/29.5.1068. PMC 29714. PMID 11222756.
  6. ^ a b "Entrez Gene: RHOBTB1 Rho-related BTB domain containing 1".

Further reading[]


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