This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified.[7]
He W, Lu Y, Qahwash I, et al. (2004). "Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation". Nat. Med. 10 (9): 959–65. doi:10.1038/nm1088. PMID15286784. S2CID23570406.
Reuter TY, Medhurst AL, Waisfisz Q, et al. (2003). "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport". Exp. Cell Res. 289 (2): 211–21. doi:10.1016/S0014-4827(03)00261-1. PMID14499622.
Geisler JG, Palmer RJ, Stubbs LJ, Mucenski ML (2000). "Nspl1, a new Z-band-associated protein". J. Muscle Res. Cell. Motil. 20 (7): 661–8. doi:10.1023/A:1005533013926. PMID10672514. S2CID26327921.
Roebroek AJ, Contreras B, Pauli IG, Van de Ven WJ (1998). "cDNA cloning, genomic organization, and expression of the human RTN2 gene, a member of a gene family encoding reticulons". Genomics. 51 (1): 98–106. doi:10.1006/geno.1997.5175. PMID9693037.
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